🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 30% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

3 Softgel(s) Serving Size
30 Servings
Other Combinations Product Type
30% Evidence Coverage

Supplement Facts — Evidence Check

✅ 1.1× RDA — within safe limits 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 600mg UL 3500mg
📊 Market median: 100.0mg (108 products)
Median 100.0mg This product: 100mg
Brain Shield
50 mg
50 mg
📊 Market median: 30.0mg (45 products)
Median 30.0mg This product: 50mg
Vinpocetine
20 mg
Leucoselect Grape extract
150 mg
BlueActiv Wild Blueberry extract
150 mg
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 125mg
✅ Within RDA (0.1× RDA of 700 mg) 📚 12 studies (Tier A: 0, B: 3)
RDA 700mg This product: 50mg UL 4000mg
Proprietary NeuroProtection Complex Blend
125 mg

Other Ingredients

Safflower Oil Gelatin Glycerin Sunflower Lecithin purified Water Sorbitol Maltodextrin Carob color Silica modified Food Starch

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (58% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: Take three (3) softgels in the morning with or without food, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS. DO NOT USE IF PREGNANT OR NURSING. Consult a physician or licensed qualified health care professional before using this product if you have, or have a family history of breast cancer, prostate cancer, prostate enlargement, heart disease, low “good” cholesterol (HDL), or if you are using any other dietary supplement, prescription drug, or over-the-counter drug.

Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms. Do not take this product if you have a history of seizures.

If you are taking anti-coagulant or anti-platelet medications, or have a bleeding disorder, consult with your healthcare provider before taking this product.

KEEP OUT OF REACH OF CHILDREN.

Do not purchase if outer seal is broken or damaged.

Additional Information

Scan for product info

Read the entire label and follow the directions carefully prior to use.

Enhances Cognitive Function*

Sharp-PS Green

To report any adverse events call 1-800-332-1088.

Store tightly closed in a cool, dry place.

Q01897G

Product Details

UPC / SKU 7 37870 18979 4
DSLD Entry Date 2016-06-24
Product Type Other Combinations
Form Softgel Capsule
DSLD ID 60562
Data Updated 2026-04-11

Research Evidence

9 Research Sources
38 Avg Quality Score
5 Rct
2 Narrative Review
2 Other
B Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial
Rct JAMA network open 2020
C Pregnenolone Reduces Stress-Induced Craving, Anxiety, and Autonomic Arousal in Individuals with Cocaine Use Disorder
Rct Biomolecules 2022
C Pregnenolone for cognition and mood in dual diagnosis patients
Rct Psychiatry research 2010
C Reduced urine pregnenolone concentration after clinical response in patients with depression: An open-label short-term prospective study
Rct Psychoneuroendocrinology 2023
C Proof-of-concept trial with the neurosteroid pregnenolone targeting cognitive and negative symptoms in schizophrenia
Rct Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009
D Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells
Other The Journal of biological chemistry 2023
D Increased steroid hormone dehydroepiandrosterone and pregnenolone levels in post-mortem brain samples of alcoholics
Other Alcohol (Fayetteville, N.Y.) 2016
D Pregnenolone sulfate in the brain: a controversial neurosteroid
Narrative Review Neurochemistry international 2008
D Individual differences in cognitive aging: implication of pregnenolone sulfate
Narrative Review Progress in neurobiology 2003
View all evidence for Pregnenolone →