For Mood With SAMe 400 mg by Vita+Apps By V — Ingredients, Evidence & Safety

Product Label

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Label Data

1 Tablet(s) Serving Size

Non-Nutrient/Non-Botanical Product Type

100% Evidence Coverage

Supplement Facts — Evidence Check

S-Adenosyl-L-Methionine

400 mg

📊 Market median: 200.0mg (52 products) 📚 10 studies (Tier A: 0, B: 6)

This product: 400mg

Other Ingredients

Cellulose Silica Magnesium Stearate Riboflavin Ethyl Cellulose Oleic Acid Medium Chain Triglycerides Sodium Alginate Modified Cellulose Triacetin Calcium Carbonate Ammonium Hydroxide

Label Claims — Verification

❓ All Other

All Other (100% of products) Structure/Function (83% of products) Nutrient (6% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

DIRECTIONS: As a dietary supplement, take one (1) tablet per day on an empty stomach, or as directed by your physician.

⚠️ Warnings & Precautions

WARNING: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

KEEP OUT OF REACH OF CHILDREN.

TAMPER EVIDENT Do not use if outer seal is broken or missing.

🧪 Formulation Notes

gluten free dairy free soy free nut free

Does not contain: Yeast, Wheat, Gluten, Sugar, Soy, Dairy, Citrus, Fish, Animal Derivatives, Preservatives or Artificial Flavors.

Additional Information

STORE IN A COOL, DRY PLACE.

Visit www.vitaminshoppe.com or call 1-888-482-9424 for more information and to reorder.

access code: FPO123456789

enteric coated

Plus premium subscription to the Pear Happy App

{tablet} actual size

Item No. VS-3407 2041713 EP 53

Product Details

UPC / SKU 7 66536 03407 9

DSLD Entry Date 2016-02-23

Product Type Non-Nutrient/Non-Botanical

Form Tablet or Pill

Brand Vita+Apps By V

DSLD ID 56339

Data Updated 2026-04-11

Research Evidence

12 Research Sources

58 Avg Quality Score

8 Meta Analysis

3 Systematic Review

1 Rct

B S-adenosyl-L-methionine for alcoholic liver diseases

Meta Analysis The Cochrane database of systematic reviews 2006

PubMed

B S-adenosyl methionine (SAMe) for depression in adults

Meta Analysis The Cochrane database of systematic reviews 2016

PubMed

B Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease

Meta Analysis Annals of the rheumatic diseases 2024

PubMed DOI

B SAMe-TT2R2 Score to Predict Time in Therapeutic Range of Vitamin K Antagonists in Asian and Non-Asian patients: A Systematic Review and Meta-analysis

Meta Analysis American journal of cardiovascular drugs : drugs, devices, and other interventions 2024

PubMed DOI

B S-Adenosylmethionine (SAMe) as an adjuvant therapy for patients with depression: An updated systematic review and meta-analysis

Meta Analysis General hospital psychiatry 2024

PubMed DOI

B S-adenosyl-L-methionine for alcoholic liver diseases

Systematic Review The Cochrane database of systematic reviews 2001

PubMed

B WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

C S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis