🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

9.2 Gram(s) Serving Size
24 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calories
15 {Calories}
Total Carbohydrates
6 Gram(s) (2% DV)
0.15 mg (10% DV)
✅ Within RDA (0.1× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 0.15mg
0.17 mg (10% DV)
✅ Within RDA (0.1× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 0.17mg
20 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
0.2 mg (10% DV)
✅ Within RDA (0.2× RDA of 1.3 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 0.2mg UL 100mg
0.6 mcg (10% DV)
✅ Within RDA (0.2× RDA of 0.0024 mg) 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.0006mg
Concentrated Calorie Burning Blend: (Combination)
Piperine
5 mg
High Energy Mind/Body Matrix {Blend}

Other Ingredients

Gum Arabic Natural and Artificial flavors Citric Acid Sucralose Silica FD&C Red #40

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years) Sugar Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, mix one ultra-concentrated scoop (9.2 g) into 10-12 fl. oz. of cold water and enjoy for an invigorating and metabolic boost. On training days, take 30-45 minutes prior to exercise. On non-training days, take one serving in the morning. Do not take prior to bedtime. For maximum body-sculpting results, use in conjunction with Total Lean(TM) Advanced Tone & define. for personalized stacking suggestions and to learn more, visit www.GNC.com/TotalLeanAdvanced.

⚠️ Warnings & Precautions

Keep out of reach of children.

Each serving provides 200 mg of caffeine.

Warning: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

🧪 Formulation Notes

Sugar Free

Calories:15 Net Carbs: 1 g Fiber: 5 g Sugar: 0 g

Each serving provides 200 mg of caffeine.

5G Fiber

Additional Information

Burn calories-Amazing taste!

Store in a cool, dry place.

G4682101

NEW

Metabolism enhancing powder High energy thermogenic

Clinically proven to burn 3x more calories Fuels fast metabolism

Natural & Artificial flavors

Clinically Studied

CODE 732229 APG

Notice: Significant product settling can occur.

In a double-blind, randomized, placebo-controlled, cross-over study, 25 subjects exercised on a treadmill on two occasions. On one occasion, the subjects took the thermogenic blend before exercise and on the second occasion, they took a placebo. When the subjects took the thermogenic blend, they burned three times more calories before, 3% more calories during and 12 times more calories after exercise compared to when they took the placebo.

Product Details

UPC / SKU 0 48107 14980 2
DSLD Entry Date 2015-07-24
Product Type Other Combinations
Form Powder
DSLD ID 47532
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

Compare Similar Products

View all Thiamine products →