🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

650 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 650mg
Plant-based Enzyme Blend
525 mg

Other Ingredients

Vegetable Capsule

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (82% of products) Nutrient (8% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: Take 1 to 2 capsules with meals as needed.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

TAMPER EVIDENT: DO NOT USE IF SAFETY SEAL IS BROKEN OR MISSING.

WARNING: Consult your physician before using this or any product if you are pregnant, nursing, trying to conceive, taking medication, or have a medical condition.

Notice: Do not use if you have gastritis, gastroesophageal reflux disease (GERD) or peptic ulcer disease. Discontinue use, if abdominal pain, nausea or vomiting occur, unless directed by your physician.

🧪 Formulation Notes

Contains no yeast, corn, gluten, salt, sugar, dairy, animal products, binders, fillers or artificial ingredients

HCl for Enhanced Digestion With SmartZYME(TM) BLend

Gluten-Free

Additional Information

HCl production decreases as you age. The HCl in Heartburn Prevention provides a missing component for proper digestion and stomach function in those individuals who product too little stomach acid.

Quality and Purity Guaranteed

MADE IN USA

Power Enzyme Formula with HCl Helps Prevent Occasional Heartburn

Store in a dry place at 59-86 (o)F (15-30(o)C).

Manufactured in a GMP and Kosher facility.

ReNewLife uses an exclusive SmartZYME blend of enzymes that represent multiple strains blended to increase the potency of the enzymes over a broader pH range. These enzymes are more broadly effective in the human digestive system.

RENEW LIFE(R) The Digestive Care Company

0410

Product Details

UPC / SKU 6 31257 53558 0
DSLD Entry Date 2014-08-26
Product Type Non-Nutrient/Non-Botanical
Form Capsule
Brand Renew Life
DSLD ID 36749
Data Updated 2026-04-11

Research Evidence

23 Research Sources
47 Avg Quality Score
18 Rct
3 Systematic Review
1 Meta Analysis
1 Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009
View all evidence for Betaine →

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