Ripped Fuel 5X by Twinlab — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
67% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size

Other Combinations Product Type

67% Evidence Coverage

Supplement Facts — Evidence Check

Thiamine

0.5 mg (33% DV)

✅ Within RDA (0.4× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 0.5mg

Niacin

10 mg (50% DV)

✅ Within RDA (0.7× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 10mg UL 35mg

Pyridoxine

0.5 mg (25% DV)

✅ Within RDA (0.4× RDA of 1.3 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 0.5mg UL 100mg

Vitamin B12

50 mcg (833% DV)

📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.05mg

Calcium

40 mg (4% DV)

Chromium

200 mcg (167% DV)

📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.2mg

Caffeine

99 mg

📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)

This product: 99mg UL 400mg

5X Potentiator Blend

130 mg

5X Thermoenergetic Blend

198 mg

Other Ingredients

Maltodextrin Cellulose Stearic Acid purified Water Croscarmellose Sodium Silica Magnesium Stearate natural Cinnamon flavor Glycerin

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DIRECTIONS: Take one tablet two times a day before a meal.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN

WARNING: Do not use if you are pregnant or nursing, if you have any chronic disease of the gastrointestinal tract, if you have any other medical condition or are taking any medication.

Consult your physician before use.

Contains chromium picolinate, which may enhance insulin sensitivity in diabetics. Contains 99 mg of caffeine. Limit use of other caffeine containing products while taking this product, as too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally, rapid heart beat.

Not intended for use by persons under the age of 18.

Additional Information

2024885

For best results, use as part of a low-fat diet and exercise program. Individual results may vary.

Increased Definition for Men & Women*

METABOLIC ACCELERATOR*

SUPER CONCENTRATED • TWO SMALL TABLETS DAILY

THE SCIENCE BEHIND THE SIZE: • PRODUCT: a super-concentrated professional-strength formula that uses five distinct nutritional mechanisms to fuel your weight loss program.* • RESULT: get ripped by reducing body fat while preserving lean muscle.* • SCIENCE: research shows that these ingredients stimulate fat loss.*

Product Details

DSLD Entry Date 2011-12-23

Product Type Other Combinations

Form Tablet or Pill

Brand Twinlab

DSLD ID 3621

Data Updated 2026-04-11

Research Evidence

100 Research Sources

56 Avg Quality Score

48 Systematic Review

30 Meta Analysis

13 Rct

6 Clinical Trial

1 Cochrane Review

1 Regulatory Source

B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol

Systematic Review The Cochrane database of systematic reviews 2013

PubMed DOI Cochrane

B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials

Systematic Review Nutritional neuroscience 2023

PubMed DOI

B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis

Meta Analysis BMJ open 2022

PubMed DOI

B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024

PubMed DOI

B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis

Systematic Review Intensive care medicine 2022

PubMed DOI

B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis

Meta Analysis Pain medicine (Malden, Mass.) 2020

PubMed DOI

B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis

Meta Analysis Critical care medicine 2021

PubMed DOI

B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2022

PubMed DOI

B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis

Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023

PubMed DOI

B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse

Systematic Review The Cochrane database of systematic reviews 2004

PubMed Cochrane

View all evidence for Thiamine →