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PLUS

product on market Other (e.g. tea bag) Mannatech Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for PLUS
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
Other Combinations
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 {Calories}
Protein
1 Gram(s)
Wild Yam extract
200 mg
L-Glutamic Acid
200 mg
Glycine
200 mg
200 mg
Market median: 500.0mg (159 products)
95 mg
Market median: 500.0mg (143 products)
Beta-Sitosterol
25 mg
Ambrotose Complex
2.5 mg
1 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Silicon Dioxide Hypromellose Calcium Carbonate Medium Chain Triglycerides Magnesium Stearate Xylitol
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Adult Use: Take one caplet with 8 fl oz of water or juice three times per day.

Warnings & Precautions

WARNING: If you are pregnant, nursing, taking medication, have a health condition or are planning a medical procedure, consult your health professional before use.

Discontinue use and consult a doctor if any adverse reaction occurs.

Do not use if inner seal is missing or broken.

Keep out of reach of children.

Keep bottle tightly closed.

Formulation Notes

Each caplet includes a proprietary blend of plant carbohydrates, herbs and amino acids.

Gluten-Free

Additional Information

PLUS

Store in a cool, dry place.

Product Number 11101 US.11101.14.021

SUPPORTS OPTIMAL ENDOCRINE HEALTH*

NSF(R) Contents Tested and Certified

M(SM)

Metadata

Product Details

DSLD Entry Date2014-07-25
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandMannatech
DSLD ID34898
Data Updated2026-04-11
Research

Research Evidence

45
Research Sources
52
Avg Quality
12
Rct
11
Systematic Review
11
Meta Analysis
11
Clinical Trial
A Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Nutritional interventions for treating foot ulcers in people with diabetes
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2007 PubMed
B The Effect of Amino Acids on Wound Healing: A Systematic Review and Meta-Analysis on Arginine and Glutamine
Meta Analysis Nutrients 2021 PubMed DOI
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute ischaemic stroke
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use
Meta Analysis Nutrients 2023 PubMed DOI
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
B An Analysis of Popular Online Erectile Dysfunction Supplements
Systematic Review The journal of sexual medicine 2019 PubMed DOI
View all evidence for L Arginine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.