🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

📸

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Label Data

3 Caplet(s) Serving Size
60 Servings
Other Combinations Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 500.0mg (143 products)
This product: 1.98mg
ACTINOS2
150 mg

Other Ingredients

Cellulose Cellulose derivatives Stearic Acid Magnesium Stearate Silica Glycerin

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (91% of products) Nutrient (35% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: Take three caplets twice per day: 3 caplets 30 minutes before breakfast and 3 caplets again 30 minutes before lunch with 8 ounces of water.

⚠️ Warnings & Precautions

Cautions: Consult your healthcare practitioner prior to use, especially if you have or suspect you have a medical condition, including diabetes or cold sores; if you take prescription drugs or are allergic to any ingredient; or if you are pregnant or lactating.

Cautions: Consult your healthcare practitioner prior to use, especially if you have or suspect you have a medical condition, including diabetes or cold sores; if you take prescription drugs or are allergic to any ingredient; or if you are pregnant or lactating.

Keep out of reach of children. This product is not intended for use by individuals under 18 years of age.

Warning: This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

Storage: Keep closed in a cool, dry place out of reach of children.

Contains: Milk

🧪 Formulation Notes

NO Max represents a patented, extended-release nitric oxide precursor. Scientists now refer to nitric oxide (NO) as the "foundation" of cardiovascular health. This tiny molecule is a vasodilator responsible for controlling blood flow to the entire body, which may help support healthy blood flow pressure and promote the health of the endothelium?—the inside of blood vessels. With age comes diminished NO levels; that's why since 1998, when three scientists won the Nobel Prize for their discovery of NO, researchers have been working to harness its heart-healthy activity. Today, with the application of HoltraCeuticals extended-release technology, that activity has been realized with NO Max.

Does not contain: Wheat, gluten, corn, years , soy, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Extended-release arginine alpha-ketoglutarate

Increases blood flow for erectyle function

Manufactured in a GMP compliant facility.

Up-regulated with: ACTINOS2 NOS-enhancing peptide fraction

Additional Information

Storage: Keep closed in a cool, dry place out of reach of children.

Holtorf Medical Group, Inc. Center for hormone imbalance, hypothyroidism and fatigue

To reorder visit Holtraceuticals.com This package is completely recyclable

Product Details

UPC / SKU 6 69439 77049 8
DSLD Entry Date 2023-01-23
Product Type Other Combinations
Form Other (e.g. tea bag)
DSLD ID 273784
Data Updated 2026-04-11

Research Evidence

45 Research Sources
52 Avg Quality Score
12 Rct
11 Systematic Review
11 Meta Analysis
11 Clinical Trial
A Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Meta Analysis The Cochrane database of systematic reviews 2017
A Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Meta Analysis The Cochrane database of systematic reviews 2017
B Nutritional interventions for treating foot ulcers in people with diabetes
Meta Analysis The Cochrane database of systematic reviews 2020
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
Systematic Review The Cochrane database of systematic reviews 2002
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2007
B The Effect of Amino Acids on Wound Healing: A Systematic Review and Meta-Analysis on Arginine and Glutamine
Meta Analysis Nutrients 2021
B Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute ischaemic stroke
Systematic Review The Cochrane database of systematic reviews 2000
B Dietary Supplements for Erectile Dysfunction: Analysis of Marketed Products, Systematic Review, Meta-Analysis and Rational Use
Meta Analysis Nutrients 2023
B Arginine supplementation for prevention of necrotising enterocolitis in preterm infants
Systematic Review The Cochrane database of systematic reviews 2004
B An Analysis of Popular Online Erectile Dysfunction Supplements
Systematic Review The journal of sexual medicine 2019
View all evidence for L Arginine →

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