🟢 85/100

This product is generally safe

  • Manganese: 16mg is 1.5× the Tolerable Upper Intake Level (11mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 57% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Manganese: 16mg is 1.5× the Tolerable Upper Intake Level (11mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Tablet(s) Serving Size
90 Servings
Other Combinations Product Type
57% Evidence Coverage

Supplement Facts — Evidence Check

4.2 mcg (175% DV)
✅ 1.8× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.004200000000000001mg
Iron
2.2 mg (12% DV)
300 mcg (200% DV)
✅ 2.0× RDA — within safe limits 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.3mg UL 1.1mg
2.7 mg (25% DV)
✅ Within RDA (0.2× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 2.7mg UL 40mg
0.3 mg (33% DV)
✅ Within RDA (0.3× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.3mg UL 10mg
16 mg (696% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.5× (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 16mg UL 11mg
Proprietary Blend
210 mg

Other Ingredients

Manganese Lactate Honey Zinc Amino Acid Chelate Iron Amino Acid Chelate Copper Amino Acid Chelate Dicalcium Phosphate Calcium Stearate Prolamine Iodine Cyanocobalamin

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: One tablet per day, or as directed.

⚠️ Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately. Keep out of reach of children.

Warning: This product should only be used under the direct supervision of a qualified health care professional.

Please consult your health care professional if you are pregnant, nursing, or taking any antithyroid medicines.

Contains: Wheat.

🧪 Formulation Notes

Tissue Health

Additional Information

Whole food supplements since 1929

Product Details

UPC / SKU 8 12122 01184 6
DSLD Entry Date 2025-09-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 340290
Data Updated 2026-04-11

Research Evidence

237 Research Sources
53 Avg Quality Score
83 Meta Analysis
74 Systematic Review
45 Rct
29 Clinical Trial
2 Guideline
2 Regulatory Source
1 Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023
View all evidence for Vitamin B12 →

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