Brain Factors
87/100
This product is generally safe
- Nicotinamide Riboside Hydrogen Malate: 415mg is 11.9× the Tolerable Upper Intake Level (35mg)
- 33% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Nicotinamide Riboside Hydrogen Malate: 415mg is 11.9× the Tolerable Upper Intake Level (35mg)
Label Data
1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Supplement Facts — Evidence Check
⚠️ Exceeds Tolerable Upper Intake Level by 11.9× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
CognatiQ
100 mg
85 mg
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
Other Ingredients
Hypromellose
Calcium Laurate
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (100% of products)
Structure/Function (90% of products)
Nutrient (28% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Suggested use: Take 1 capsule daily or as recommended by your health-care practitioner.
⚠️ Warnings & Precautions
Tamper evident: Use only if bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
🧪 Formulation Notes
Healthy aging Brain/Nerves
Gluten free
Coffee fruit extract and nicotinamide riboside
Additional Information
Store tightly sealed in a cool, dry place.
T Exclusive
Manufactured in the USA using US & Imported ingredients NSF Contents Certified
Product Details
Research Evidence
10
Research Sources
49
Avg Quality Score
8
Rct
1
Systematic Review
1
Clinical Trial
B
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
C
The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials
C
Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.
C
Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
C
Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
C
Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
C
Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI
C
Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
C
A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.
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