Betaine HCl+

product on market Capsule Enzyme Science 🟢 Safety: 100/100
Brand: Enzyme Science
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

Label for Betaine HCl+
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Label Data

1 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

1300 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 1300mg
Protease
Mucosave FG
50 mg

Other Ingredients

Hydroxypropyl Methylcellulose Water Rice Concentrate

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (100% of products) Structure/Function (82% of products) Nutrient (8% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Recommended Dose: Take 1 capsule 1-2 times daily with meals. More may be taken as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

Consult a physician before use if you are pregnant or nursing, taking medications or have a medical condition.

🧪 Formulation Notes

With HCl and an acid-active vegan protease, plus Mucosave FG. Gentle formula includes an acid-active vegan protease (active at a low pH), plus Mucosave FG, a clinically studied blend of prickly pear and olive leaf extracts shown to protect and soothe the stomach lining and boost digestion.

Betaine HCl+ offers betaine hydrochloride for occasional heartburn and indigestion due to low stomach acid.

Do not use if safety seal is broken or missing.

For occasional heartburn and indigestion Soothes discomfort Boosts digestion

Protease + Mucosave FG

Vegan

Gluten-free Contains no: Casein, crustaceans, eggs, fish, gluten, milk, nuts, sesame, shellfish, soy, wheat; artificial colors, fillers or flavors Non-GMO

Additional Information

Keep out of reach of children.

Scan for protocol Practitioner division of Enzymedica

Product Details

UPC / SKU 6 70480 30034 3
DSLD Entry Date 2025-07-24
Product Type Other Combinations
Form Capsule
Brand Enzyme Science
DSLD ID 334816
Data Updated 2026-04-11

Research Evidence

23 Research Sources
47 Avg Quality Score
18 Rct
3 Systematic Review
1 Meta Analysis
1 Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016
PubMed DOI
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009
PubMed DOI
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017
PubMed DOI
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015
PubMed DOI
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023
PubMed DOI
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019
PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
PubMed DOI
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN
PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
PubMed DOI
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009
PubMed DOI
View all evidence for Betaine →

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