🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
57% Evidence Coverage

Supplement Facts — Evidence Check

2 mg
📊 Market median: 3.0mg (984 products) 📚 236 studies (Tier A: 2, B: 109)
This product: 2mg UL 10mg
Lemon Balm Herb Top Extract
125 mg
100 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 100mg
📊 Market median: 300.0mg (214 products) 📚 23 studies (Tier A: 0, B: 6)
This product: 56mg
📊 Market median: 250.0mg (60 products) 📚 7 studies (Tier A: 0, B: 1)
This product: 50mg
Skullcap Herb Top Extract
50 mg
Gamma-Aminobutyric Acid
50 mg

Other Ingredients

Microcrystalline Cellulose Magnesium Stearate Maltodextrin Hypromellose

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (7% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Adults - Take 1 to 2 capsules per day or as directed by a healthcare professional. Take a single dose 30 to 60 minutes at or before bedtime. Take an earlier dose during the evening if necessary. For Jet Lag: Take once a day at bedtime, while travelling, and at destination until adapted to the new time zone/or daily pattern. Duration of use: Consult a healthcare professional for use beyond 4 weeks.

⚠️ Warnings & Precautions

Contraindications: Do not use this product if you are pregnant or breastfeeding. Consult a healthcare professional prior to use, especially if you are taking medications to suppress the immune system (immunosuppressive medications) or to affect mental state or increase sedation, steroids or blood thinners, or if you have cardiovascular, immune, liver or chronic kidney disease. Consult a healthcare professional prior to use if you are taking medications for seizure or blood pressure, if you have hormonal or seizure disorders, asthma, depression, diabetes, low blood sugar, or migraine.

Do not drive or use machinery for 5 hours after taking melatonin. Warnings: Do not use if safety seal is broken. Consult a healthcare professional if symptoms persist or worsen or if sleeplessness persists continuously for more than 4 weeks (chronic insomnia). Consumption with alcohol, other medications or health products with sedative properties is not recommended. Known adverse reactions: Some people may experience drowsiness. Exercise caution if operating heavy machinery, driving a motor vehicle or involved in activities requiring mental alertness. Stop use if hypersensitivity/allergy occurs or if you experience headache, confusion, or nausea.

🧪 Formulation Notes

Made in Canada

Sleep-Matrix Melatonin With Nervine Herbs

Indications: Helps to speed up the time it takes to fall asleep in people who fall asleep slowly and helps to temporarily promote relaxation. Helps increase the total sleep time in people suffering from sleep restriction or altered sleep schedule (e.g. shift-work and jet lag). Helps re-set the body's sleep-wake cycle and prevent or reduce the effects of jet lag (e.g. daytime fatigue, sleep disturbance).

Vegan.

GMO, gluten, soy and dairy free.

Additional Information

NPN 80111589 Peel for more information

Product Details

UPC / SKU 8 71740 00173 8
DSLD Entry Date 2025-09-25
Product Type Other Combinations
Form Capsule
Brand Cyto-Matrix
DSLD ID 334485
Data Updated 2026-04-11

Research Evidence

291 Research Sources
55 Avg Quality Score
129 Meta Analysis
93 Systematic Review
51 Rct
11 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Interventions for preventing delirium in hospitalised non-ICU patients
Meta Analysis The Cochrane database of systematic reviews 2016
A Melatonin for preoperative and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2020
A Effect of melatonin on quality of life and symptoms in patients with cancer: a systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ open 2022
B Pharmacological interventions for prevention of weight gain in people with schizophrenia
Meta Analysis The Cochrane database of systematic reviews 2022
B Melatonin for pre- and postoperative anxiety in adults
Meta Analysis The Cochrane database of systematic reviews 2015
B Prevention of depression in adults with long-term physical conditions
Meta Analysis The Cochrane database of systematic reviews 2021
B Comparative effects of pharmacological interventions for the acute and long-term management of insomnia disorder in adults: a systematic review and network meta-analysis
Systematic Review Lancet (London, England) 2022
B Does melatonin administration reduce the incidence of postoperative delirium in adults? Systematic review and meta-analysis
Meta Analysis BMJ open 2023
B Second-generation antidepressants for preventing seasonal affective disorder in adults
Meta Analysis The Cochrane database of systematic reviews 2015
B Interventions for preventing type 2 diabetes in adults with mental disorders in low- and middle-income countries
Meta Analysis The Cochrane database of systematic reviews 2021
View all evidence for Melatonin →

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