SAMe

product on market Tablet or Pill OmneDiem Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for SAMe
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
30
Servings
Non-Nutrient/Non-Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 500.0mg (193 products) 7 studies — no high-quality reviews

Other Ingredients

Microcrystalline Cellulose Crospovidone Silicon Dioxide, Colloidal Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 1-2 tablets per day or as recommended by your healthcare provider.

Warnings & Precautions

Storage: Keep closed in a cool, dry place out of reach of children.

Do not use if tamper seal is damaged.

Formulation Notes

S-Adenosylmethionine

Joint comfort Mood support Liver health

OmneDiem SAMe delivers the highest S,S isomer purity and bioavailability on the market, thanks to our proprietary natural fermentation process. Our enteric-coated tablets feature a natural plant-based coating with absolutely no synthetic copolymers or plasticizers.

Our enteric-coated tablets feature a natural plant-based coating with absolutely no synthetic copolymers or plasticizers.

Tablets are sealed immediately in superior tamper-resistant blister packaging to further ensure optimum stability.

Manufactured in a GMP compliant facility.

Vegetarian Tabs

Vegetarian Tabs

Does not contain: Sugar, starch, artificial flavors, preservatives, sodium, wheat, gluten, corn, soy, dairy, yeast, lactose, artificial colors, or plasticizers.

Additional Information

Storage: Keep closed in a cool, dry place out of reach of children.

This package is completely recyclable

Metadata

Product Details

UPC / SKU8 50023 77706 5
DSLD Entry Date2025-07-24
Product TypeNon-Nutrient/Non-Botanical
FormTablet or Pill
DSLD ID334398
Data Updated2026-04-11
Research

Research Evidence

12
Research Sources
58
Avg Quality
8
Meta Analysis
3
Systematic Review
1
Rct
B S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B S-adenosyl methionine (SAMe) for depression in adults
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed
B Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease
Meta Analysis Annals of the rheumatic diseases 2024 PubMed DOI
B SAMe-TT2R2 Score to Predict Time in Therapeutic Range of Vitamin K Antagonists in Asian and Non-Asian patients: A Systematic Review and Meta-analysis
Meta Analysis American journal of cardiovascular drugs : drugs, devices, and other interventions 2024 PubMed DOI
B S-Adenosylmethionine (SAMe) as an adjuvant therapy for patients with depression: An updated systematic review and meta-analysis
Meta Analysis General hospital psychiatry 2024 PubMed DOI
B S-adenosyl-L-methionine for alcoholic liver diseases
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
C S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis
Meta Analysis PloS one 2015 PubMed DOI
C S-Adenosylmethionine (SAMe) for Liver Health: A Systematic Review
Systematic Review Nutrients 2024 PubMed DOI
C SAMe-TT2R2 to Predict Clinical Outcomes and Time in Therapeutic Range in Patients on Vitamin K Antagonists: A Systematic Review and Meta-Analysis
Meta Analysis The Annals of pharmacotherapy 2024 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.