🟢 87/100

This product is generally safe

  • Folinic Acid: 4mg is 4.0× the Tolerable Upper Intake Level (1.0mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folinic Acid: 4mg is 4.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Caplet(s) Serving Size
90 Servings
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

50 mg (2750% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
4 mg (944% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 4.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 4mg UL 1.0mg
2 mg (40083% DV)
📊 833.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 2mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Magnesium Stearate Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Dosage and administration One caplet daily or as prescribed by a physician.

⚠️ Warnings & Precautions

Warning: In case of accidental overdose, call a doctor or poison control center immediately.

Keep this and all drugs out of the reach of children.

🧪 Formulation Notes

Allergen statement: This product contains none of the 8 major allergens (dairy, egg, fish, shellfish, tree nuts, peanuts, soy or gluten).

Vitamin B6, B9 & B12

Dye free Expect milk variations in color from shade of yellow to light pink.

Additional Information

Store at controlled room temperature 15 degrees - 30 degrees C (59 degrees - 86 degrees F)

Made in the USA

66594-692-90

Product Details

UPC / SKU 3 66594 69290 9
DSLD Entry Date 2025-06-25
Product Type Vitamin
Form Other (e.g. tea bag)
Brand Pro-Pharma
DSLD ID 330828
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
View all evidence for Vitamin B6 →

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