🟢 80/100

This product is generally safe

  • Nicotinamide Adenine Dinucleotide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Nicotinamide Adenine Dinucleotide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 500mg UL 35mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 102.5mg

Other Ingredients

Methylcellulose Microcrystalline Cellulose Sunflower Lecithin

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: Adults take 2 capsules daily, or as recommended by your healthcare practitioner, with 8 ounces of water or your favorite beverage. May be taken with or without food.

⚠️ Warnings & Precautions

Caution: Do not exceed recommended dose. Discontinue use two weeks prior to surgery.

Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children and pets.

Please use caution if you have allergies or sensitivities to any of the listed ingredients. This product is manufactured in a facility that processes fish and tree nuts.

Do not use if product has been opened or tampered with in any way. Keep out of reach of children and pets.

Keep out of reach of children and pets.

🧪 Formulation Notes

Bioavailable NAD + Trimethylglycine Essential Phospholipids

Vegan

Non-GMO Soy-free Dairy-free Gluten-free

cGMP Certified Manufacturing

Nicotinamide Adenine Dinucleotide Trimethylglycine

Enhanced absorption

Additional Information

Ln 22.2302.05L Feel Different

HDPE BPS-Free Please recycle Bottle & Cap Please take off the label Scan for info

Questions? Codeage.com

Store in a cool, dry place.

Product Details

UPC / SKU 8 50049 60902 9
DSLD Entry Date 2025-02-23
Product Type Non-Nutrient/Non-Botanical
Form Capsule
Brand Codeage
DSLD ID 328898
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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