High Potency Betaine HCl with Pepsin 650 mg

product on market Capsule Solaray 🟢 Safety: 100/100
Brand: Solaray
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 VegCap(s) Serving Size
250 Servings
Non-Nutrient/Non-Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

650 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 650mg
Pepsin
100 mg

Other Ingredients

Cellulose Rice Flour Magnesium Stearate Maltodextrin

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (100% of products) Structure/Function (82% of products) Nutrient (8% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Use only as directed. Take 1 VegCap during each meal with a glass of water. Do not exceed 12 capsules per day.

⚠️ Warnings & Precautions

Warning: Do not use if safety seal if broken or missing.

Keep out of reach of children.

Keep your licensed health care practitioner informed when using this product. Do not take this product when your meal consists only of salad or fruit. If you have hyper (high) acid stomach or ulcers, consult a physician before using this product.

Do not exceed 12 capsules per day.

🧪 Formulation Notes

High potency + Digestive health

Betaine HCl with Pepsin

Discussion: This product contains Hydrochloric acid and an enzyme called pepsin, both of which are naturally produced in the stomach to aid in digestion. Pepsin, a protein digesting enzyme derived from porcine, is known to have an off odor when exposed to heat and moisture. This is not an indication of spoilage.

Additional Information

Lab Verified

Since 1973, we've scoured the globe for the highest quality ingredients, connecting you with the most efficacious supplements that help you live brighter & embrace the moments that matter most.

Store in a cool, dry place.

Store in a dry, cool place.

Product Details

UPC / SKU 0 76280 04815 5
DSLD Entry Date 2025-02-23
Product Type Non-Nutrient/Non-Botanical
Form Capsule
Brand Solaray
DSLD ID 325990
Data Updated 2026-04-11

Research Evidence

23 Research Sources
47 Avg Quality Score
18 Rct
3 Systematic Review
1 Meta Analysis
1 Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016
PubMed DOI
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009
PubMed DOI
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017
PubMed DOI
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015
PubMed DOI
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023
PubMed DOI
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019
PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
PubMed DOI
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN
PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
PubMed DOI
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009
PubMed DOI
View all evidence for Betaine →

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