100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6 · grounded in 1 source
· methodology
Citicoline is researched for its role in supporting cognitive function and phospholipid synthesis in the brain. There is moderate evidence suggesting it may assist with memory and focus. However, the overall evidence coverage for this specific formulation is limited.
AI-generated summary based on research evidence. Not medical advice.
Details
Label Data
1 Capsule(s)
Serving Size
Non-Nutrient/Non-Botanical
Product Type
Ingredients
Supplement Facts — Evidence Check
Within RDA (0.5× RDA)
38 studies (A:1, B:7)
Other Ingredients
Gelatin
Rice Flour
Silicon Dioxide
Magnesium Stearate
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
Suggested use: As a dietary supplement, adults take one (1) capsule daily, preferably with a meal or as directed by a health care professional.
Warnings & Precautions
Caution: If you are pregnant, nursing, taking any medication(s) or have any medical condition, consult your doctor before use.
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Do not use if safety seal is damaged or missing.
Formulation Notes
Cognitive Health Support
Promotes brain health
Supports memory, focus & clarity
Supports learning & cognitive functions
Contains no: Preservatives, artificial colors, flavors or sweeteners, sugar, starch, milk, lactose, gluten, wheat, yeast, fish or sodium.
An FDA regulated facility
Additional Information
Store in a cool, dry place.
Visit us online @ purenaturals.co
Made in USA
Sourced from a GMP Certified Facility Good Manufacturing Practice Quality Assured
Metadata
Product Details
UPC / SKU8 16511 02286 4
DSLD Entry Date2025-01-23
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
Data Updated2026-04-11
Research
Research Evidence
B
Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis
Biological psychiatry. Cognitive neuroscience and neuroimaging
2024
PubMed
DOI
B
Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline
Briefings in bioinformatics
2026
PubMed
DOI
B
Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline
Journal of gastroenterology
2022
PubMed
DOI
B
Scientific Opinion on health claims related to choline
Regulatory Source
EFSA Journal
2011
DOI
C
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis
Nutrition reviews
2022
PubMed
DOI
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review
Psychotherapy and psychosomatics
2013
PubMed
DOI
C
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct
The British journal of nutrition
2007
PubMed
C
Differential metabolism of choline supplements in adult volunteers.
View all evidence for Choline →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.
