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Joint Replete

product on market Capsule NuMedica Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 25% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines MSM and chondroitin sulfate, which have moderate evidence for supporting joint structure and comfort. Vitamin C and manganese act as essential cofactors for collagen synthesis. Overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Joint Replete
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
25%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
75 mg (83% DV)
10 mg (435% DV)
4.3× RDA — above typical dose (UL: 11 mg) 9 studies — no high-quality reviews
ETArol
1040 mg
Market median: 1000.0mg (2 products)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Avocado/Soybean Unsaponifiables
100 mg
Market median: 100.0mg (173 products)

Other Ingredients

Hydroxypropylmethylcellulose Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take four capsules once per day or as directed by your healthcare practitioner.

Warnings & Precautions

Caution: Keep out of reach of children.

Persons with a known allergy to shellfish should not use this product.

Contains: Shellfish (crab, shrimp, lobster, crayfish) derivatives, soy.

Formulation Notes

Joint Replete is a comprehensive joint and soft tissue support formula featuring ETArol- the highest quality, whole green-lipped mussel extract from New Zealand. It also contains glucosamine‚ chondroitin sulfate and MSM‚ as well as manganese‚ which aids in the growth and development of normal bone and in the formation of mucopolysaccharides. Additionally this formula contains hyaluronic acid, a powerful antioxidant which promotes resiliency and protects against repetitive wear and tear.. The whole Green-Lipped Mussel extract contains naturally occurring oils and glycosaminoglycans‚ the principal component of cartilage and synovial fluid found in the joints.

ETArol is a premium quality whole green-lipped mussel extract produced by proprietary cold processing should and not be confused with inferior‚ oil-based lipid extracts commonly used in joint health dietary supplements.

This formula meets or exceeds a cGMP Quality Standards.

Does not contain: Milk, eggs, fish, tree nuts, peanuts, wheat.

Professional quality formulas

Featuring ETArol New Zealand Green-lipped mussel extract

Joint & soft tissue support

GF Gluten-Free

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU8 12527 01067 3
DSLD Entry Date2025-01-23
Product TypeOther Combinations
FormCapsule
DSLD ID323550
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
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Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.