Dual-Tox DPO

product on market Capsule NuMedica 🟢 Safety: 97/100
Brand: NuMedica
🟢 97/100

This product looks safe

  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 69% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

4 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
69% Evidence Coverage

Supplement Facts — Evidence Check

50 mg (2941% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
680 mcg DFE (170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 680mg UL 1.0mg
200 mcg (8333% DV)
📊 83.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.2mg
Artichoke Aerial Part Extract
600 mg
Watercress Whole Herb Extract
500 mg
250 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 250mg
200 mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 200mg
200 mg
📊 Market median: 600.0mg (7 products) 📚 39 studies (Tier A: 2, B: 13)
This product: 200mg
200 mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 200mg
150 mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 150mg
100 mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
100 mg
📊 Market median: 1000.0mg (2 products)
This product: 100mg
100 mg
📊 Market median: 250.0mg (182 products) 📚 10 studies (Tier A: 0, B: 2)
This product: 100mg

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose Silicon Dioxide

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take four capsules once per day or as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Caution: Keep out of reach of children.

🧪 Formulation Notes

Dual-Tox DPO is designed to support balanced activity of the body's Phase I and Phase II detoxification processes. It has been formulated to contain select ingredients, Dual Phase Optimizers (DPO), to enhance the activities of hepatic detoxification pathways.

The 5-MTHF in this formula - Quatrefolic -is the most biologically active form of folate, allowing rapid uptake into the bloodstream.

Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy.

This formula meets or exceeds cGMP quality standards.

Rapid uptake 5-MTHF Bioactive Folate Activated B-Vitamins

Vegetarian

GF Gluten-Free

Professional quality formulas Dual Phase Optimizers to support Phase I & II detoxification

Dual-Tox DPO featuring 5-MTHF as Quatrefolic

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 8 12527 01023 9
DSLD Entry Date 2025-03-25
Product Type Other Combinations
Form Capsule
Brand NuMedica
DSLD ID 323528
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
PubMed Cochrane
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
PubMed DOI
View all evidence for Vitamin B6 →

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