Endefen

product on market Powder Metagenics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 14% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains Vitamin C, which has strong evidence for supporting immune function and antioxidant activity. The remaining components are basic macronutrients providing foundational caloric energy. Overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Endefen
Open Full PDF View on NIH DSLD →
Details

Label Data

7.5 Gram(s)
Serving Size
56
Servings
Other Combinations
Product Type
14%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
30 Calorie(s)
Total Fat
1 Gram(s) (1% DV)
Total Carbohydrates
5 Gram(s) (2% DV)
Protein
1 Gram(s)
Vitamin C
150 mg (167% DV)
Sodium
5 mg (1% DV)
Apple, Powder
1 Gram(s)
Plantain, Powder
1 Gram(s)
Arabinogalactans
750 mg
500 mg
Market median: 60.0mg (94 products) 13 studies (A:0, B:7)
Chinese Cinnamon, Powder
350 mg
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
D-Mannose
125 mg
250 mcg
Market median: 4.0mg (47 products)

Other Ingredients

Rice Bran Xylitol Rice Syrup, Solids Natural Flavors
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Mix about one level tablespoon (7.5 g) in two to four ounces of juice or water once daily, or as directed by your healthcare practitioner.

Warnings & Precautions

Caution: If pregnant or nursing, or taking medication, consult your healthcare practitioner before use.

Keep out of the reach of children.

Practitioner Exclusive

Formulation Notes

Endefen is uniquely designed to nutritionally support the healthy function of the gastrointestinal (GI) tract. This exceptional formula addresses multiple factors that contribute to GI health. Supports the integrity of the gastric lining by promoting the growth of gastric mucosal cells.

Lecithin and astaxanthin have demonstrated protective effects on the gastric environment. Green tea and arabinoglactans may-help promote the growth of healthy intestinal microflora. Arabinogalactans may help promote the production of beneficial short-chain fatty acids, an important fuel for intestinal cells. Plantain has been shown in a lab setting to support the integrity of the gastric lining. Targeted antioxidants help protect the gastric mucosa.

Key nutrients help to support GI immune function.

This product is non-GMO and gluten-free.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Multi-dimensional GI support & protection

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 55571 01505 1
DSLD Entry Date2025-02-23
Product TypeOther Combinations
FormPowder
DSLD ID323351
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.