🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
180 Servings
Non-Nutrient/Non-Botanical Product Type
0% Evidence Coverage

Supplement Facts — Evidence Check

200 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 200mg
Ox Bile extract
100 mg
Papaya fruit powder
45 mg
Pancreatin 11X:
134 mg
40 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 40mg
Acid Protease
10 mg
Papain
2 mg
Cellulase
0.1 mg

Other Ingredients

Microcrystalline Cellulose Gelatin Magnesium Stearate Silicon Dioxide

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (82% of products) Nutrient (8% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 capsule with a meal.

⚠️ Warnings & Precautions

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Caution: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication (especially blood thinners), or have a medical condition (including allergy to papaya, pineapple).

Consult physician if pregnant/nursing, taking medication (especially blood thinners), or have a medical condition (including allergy to papaya, pineapple).

Contains sulfites.

🧪 Formulation Notes

NOW Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion. Formulated with Bromelain, Ox Bile, Pancreatin and Papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Natural color variation may occur in this product.

Supports healthy digestion Breaks down fats, carbs & protein Optimizes nutrient availability

Made and quality tested in the USA with globally sourced ingredients.

Additional Information

Digestive Family owned since 1968.

Store in a cool, dry place after opening.

GMP Quality Assured

Product Details

UPC / SKU 7 33739 02964 5
DSLD Entry Date 2024-06-20
Product Type Non-Nutrient/Non-Botanical
Form Capsule
Brand NOW
DSLD ID 314091
Data Updated 2026-04-11

Research Evidence

23 Research Sources
47 Avg Quality Score
18 Rct
3 Systematic Review
1 Meta Analysis
1 Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009
View all evidence for Betaine →

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