🟢 97/100

This product looks safe

  • Niacin: 338mg is 9.7× the Tolerable Upper Intake Level (35mg)
  • 33% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 338mg is 9.7× the Tolerable Upper Intake Level (35mg)

Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

338 mg (1690% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 9.7× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 338mg UL 35mg
Phytosterol Complex
150 mg
Guar Gum
50 mg
Lecithin Complex
450 mg
Complex
175 mg
68 mg
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 68mg UL 3500mg
75 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 75mg
500 MCU
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 500mg
Papain
50 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 50mg
5 mg
📊 Market median: 500.0mg (19 products)
This product: 5mg
Synergistically Balanced Proprietary Blend
150 mg

Other Ingredients

Cellulose Vegetable Stearate Silica

Label Claims — Verification

All Other
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Usage: As a dietary supplement, adults take 2 tablets twice daily or as directed by your healthcare professional.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

🧪 Formulation Notes

This product contains NO yeast, wheat, gluten, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)/15(0)-25(0)C) (35-65% relative humidity)

Formula #81158

Product Details

UPC / SKU 3 10539 00895 9
DSLD Entry Date 2014-03-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 30951
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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