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5-HTP 100 mg

product on market Capsule Everyday Health Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 80% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

5-HTP is supported by moderate evidence for mood regulation, while magnesium and zinc contribute to neurological and metabolic function. Niacin and pyridoxine serve as essential cofactors in neurotransmitter synthesis. Overall, the evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for 5-HTP 100 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
90
Servings
Other Combinations
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
230 mg (32% DV)
Within RDA (0.5× RDA)
10 mg (63% DV)
Within RDA (0.7× RDA) 196 studies (A:5, B:63)
2 mg (125% DV)
1.5× RDA — within safe limits 114 studies (A:3, B:35)
4 mg (45% DV)
Within RDA (0.4× RDA) 263 studies (A:6, B:134)

Other Ingredients

Vegetarian capsule shell Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults, take up to 3 capsules per day.

Warnings & Precautions

Keep out of reach of children

Caution: Check with your doctor first if you are already taking other supplements or drugs. If you are currently taking, or within the last 90 days have taken, any anti-stress, anti-anxiety, weight-control drugs, other serotonin-modifying agents, or anti-depression medications, do not take 5-HTP supplementation without first consulting your physician.

Formulation Notes

Enhanced Serotonin support

5-HTP 100 mg + co-factors

100% Vegan

Additional Information

Store cool and dry

GMP Good Manufacturing Practice

Metadata

Product Details

UPC / SKU9 421902 427145
DSLD Entry Date2024-01-24
Product TypeOther Combinations
FormCapsule
BrandEveryday Health
DSLD ID306063
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.