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Best-Rest Formula

product on market Capsule Pure Encapsulations Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 67% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula combines melatonin and GABA, which have moderate evidence for supporting sleep onset and quality. Valerian root and Suntheanine are included to promote relaxation, though research on their efficacy varies. Vitamin B6 supports neurotransmitter synthesis, contributing to the overall sleep-supportive profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Best-Rest Formula
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

3.3 mg (194% DV)
2.5× RDA — within safe limits 114 studies (A:3, B:35)
1 mg
Market median: 3.0mg (984 products) 240 studies (A:2, B:109)
Gamma-Aminobutyric Acid
300 mg
50 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
Lemon Balm Leaf Extract
150 mg
Hops Aerial Parts Extract
150 mg
Market median: 250.0mg (60 products) 7 studies (A:0, B:1)
Market median: 400.0mg (142 products) 10 studies (A:0, B:2)

Other Ingredients

Cellulose Water Plant Fiber Gum Arabic Maltodextrin Ascorbyl Palmitate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: As a dietary supplement, take 2 capsules 30-60 minutes before bedtime.

Warnings & Precautions

Warning: see side panel Use only if safety seal is intact.

Keep out of the reach of children.

Warning: Consult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication. This product may be contraindicated for individuals taking corticosteroids.

Do not drive or operate machinery when taking melatonin.

Warning: Consult a healthcare professional if you are experiencing long-term sleep difficulties, before use in children, before use in pregnant or lactating women, those with a medical condition, and those taking medication.

Formulation Notes

Certified Gluten-Free by the Gluten-Free Certification Organization, www.gluten.org

Promotes restful sleep

Gluten-free, Non-GMO & Hypoallergenic

Gluten-free, Non-GMO & Hypoallergenic

Natural color variations can occur. Product can range from grey to light brown.

Additional Information

Store in a cool, dry place.

Scan to learn about our hypoallergenic supplements Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

GFCO.org (Gluten-Free Certification Organization)

Metadata

Product Details

UPC / SKU7 66298 01096 0
DSLD Entry Date2023-08-23
Product TypeOther Combinations
FormCapsule
DSLD ID293903
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.