🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 38% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

3 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
38% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 500mg
📊 Market median: 600.0mg (7 products) 📚 39 studies (Tier A: 2, B: 13)
This product: 100mg
L-Glutathione
100 mg
Bupleurum Root Concentrate
100 mg
Grapeseed extract
100 mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 100mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 100mg
Scute Root Concentrate
50 mg
Pueraria Root Concentrate
50 mg
50 mg
📊 Market median: 650.0mg (87 products) 📚 1 studies — no high-quality reviews
This product: 50mg
30 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 30mg
30 mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 30mg
30 mg
📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 30mg

Other Ingredients

Gelatin Rice Flour

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Recommended use: Take 1 serving (3 capsules) with water or your favorite beverage in the morning or mid-day before lunch. To maximize results, drink at least 64 ounces of water daily while using this product.

⚠️ Warnings & Precautions

Warning: Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.

Do not use if seal is broken.

🧪 Formulation Notes

Comprehensive liver health and detox formula Liver Optima is a carefully formulated blend of botanical extracts and antioxidants designed to be comprehensive solution for natural liver support and detoxification.

Each of its ingredients contribute unique properties that fortify the body and help support optimum liver health.

Milk thistle has been shown in numerous clinical studies to support healthy liver function. N-acetyl cysteine (NAC) and L-methionine are two amino acids well known for their ability to enhance glutathione production in the liver. Glutathione is a major antioxidant that plays an essential role in liver detoxification.

13 active detoxifying ingredients Promote optimal liver health Protects against free-radicals Stabilize metabolism Antioxidants protect your liver Antioxidants protect healthy cells from harmful free radicals and other toxins that build up in your body. Free radicals are molecules are that can cause damage to healthy cells and make them unstable. Neutralizing free radicals is an important part of detoxification.

Health essentials Ultra pure ingredients

Ultra micronized Max bioavailability Rejuvenating botanical formula Support healthy liver function Detoxification and cleansing 13 active detoxification ingredients

Pharmaceutical grade

High-performance liquid chromatography (HPLC) verified

Additional Information

Nutrakeyhealth.com Follow us free giveaways Facebook Pinterest Instagram Twitter #MakeLifeBetter

Pure nutrition Go green

Made in the USA

Product Details

UPC / SKU 4 56355 73413 6
DSLD Entry Date 2023-06-22
Product Type Other Combinations
Form Capsule
Brand NutraKey
DSLD ID 287416
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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