SAMe 200 mg
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
What the Evidence Says
AI-generated · Qwen 3.6 · grounded in 1 source · methodologySAMe is used to support mood regulation and joint health. Research provides moderate evidence for its efficacy in managing depressive symptoms, though clinical data for other uses remains limited. The ingredient profile maintains a high safety rating for most healthy adults.
AI-generated summary based on research evidence. Not medical advice.
Product Label
Label Data
Supplement Facts — Evidence Check
Other Ingredients
Label Claims — Verification
Product Information
Directions for Use
Suggested usage (for adults only): Take on an empty stomach during the day: For mood balance 1-4 tablets 2 times per day or as directed by a health professional. For joint support: 1-3 tablets 2 times per day or as directed by a health professional. Do not exceed a total of 8 tablets per day. For best results, take SAMe for a minimum of 2 weeks, at which time effects should be observed.
Warnings & Precautions
Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery.
Individuals with bipolar or depression, anxiety disorders, or taking antidepressant medication should consult with their health professional prior to use.
Keep out of the reach of children.
Sealed for your protection. Do not use if seal is broken.
Formulation Notes
SAMe supports mood and has a positive effect on emotional well-being. It also maintains joint health. Natural Factors SAMe is released slowly.
Manufactured to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.
Contains no artificial colors, preservatives, or sweeteners; no dairy, wheat, gluten, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.
Suitable for vegetarians/vegans.
PRODUCT OF U.S.A.
Mood & joint support
Additional Information
ISURA Non-GMO Mass Spec Documentation Lab tested
For freshness, store in a cool, dry place. For optimum freshness, refrigerate after opening.
Recyclable container and label.
Product Details
Research Evidence
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.