🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 21% of ingredients have research evidence
B Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

3 Tablet(s) Serving Size
20 Servings
Botanical with Nutrients Product Type
21% Evidence Coverage

Supplement Facts — Evidence Check

Calories
15 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
Iron
0.6 mg (3% DV)
Sodium
10 mg (1% DV)
Proprietary Blend
858 mg
Green Beet powder
300 mg
Artichoke Leaf Extract
180 mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 150mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 150mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 120mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 105mg
Boldo Leaf Extract
105 mg
Celandine Herb Extract
90 mg
Fringe Tree, Powder
90 mg
Phyllanthus amarus Aerial Parts Extract
66 mg
Picorhiza Root Extract
66 mg
📊 Market median: 650.0mg (87 products) 📚 1 studies — no high-quality reviews
This product: 66mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 60mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 60mg

Other Ingredients

Microcrystalline Cellulose Silicon Dioxide Maltodextrin Croscarmellose Sodium Hydroxypropyl Cellulose Magnesium Stearate Stearic Acid Dextrin Alginic Acid Sodium Carboxymethylcellulose Dextrose Sodium Citrate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: (Adults) For optimal dosing, take three (3) tablets twice daily. For best results, drink 8-10 glasses of water per day.

⚠️ Warnings & Precautions

Usage Warnings: Do not use if safety seal is broken.

Check with your doctor before using this product if you are using medication or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.

Do not exceed recommended daily intake.

Not intended for use by persona under 18. Keep out of reach of children.

Warning: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

Contains: Soy

🧪 Formulation Notes

Supports detoxification Supports liver health & detoxification pathways Powerful antioxidant Protection for the liver

No artificial colors or preservatives.

Additional Information

Store in a cool, dry place.

Available in fine health food stores everywhere

Product Details

DSLD Entry Date 2023-05-24
Product Type Botanical with Nutrients
Form Tablet or Pill
DSLD ID 277722
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
View all evidence for Milk Thistle →

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