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Milk Thistle Liver Cleanse

product on market Tablet or Pill Nature's Secret Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 21% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The proprietary blend contains milk thistle, which has moderate evidence for supporting liver function and protecting hepatocytes. Other listed components are basic nutrients and minerals with limited direct impact on liver detoxification. Research suggests these ingredients are generally well-tolerated and safe for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Milk Thistle Liver Cleanse
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Tablet(s)
Serving Size
20
Servings
Botanical with Nutrients
Product Type
21%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
15 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
Iron
0.6 mg (3% DV)
Sodium
10 mg (1% DV)
Proprietary Blend
858 mg
Green Beet powder
300 mg
Artichoke Leaf Extract
180 mg
Market median: 300.0mg (159 products)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
Market median: 500.0mg (234 products) 95 studies (A:0, B:35)
Boldo Leaf Extract
105 mg
Celandine Herb Extract
90 mg
Fringe Tree, Powder
90 mg
Phyllanthus amarus Aerial Parts Extract
66 mg
Picorhiza Root Extract
66 mg
Market median: 650.0mg (87 products) 1 studies — no high-quality reviews
Market median: 300.0mg (159 products)
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Microcrystalline Cellulose Silicon Dioxide Maltodextrin Croscarmellose Sodium Hydroxypropyl Cellulose Magnesium Stearate Stearic Acid Dextrin Alginic Acid Sodium Carboxymethylcellulose Dextrose Sodium Citrate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: (Adults) For optimal dosing, take three (3) tablets twice daily. For best results, drink 8-10 glasses of water per day.

Warnings & Precautions

Usage Warnings: Do not use if safety seal is broken.

Check with your doctor before using this product if you are using medication or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.

Do not exceed recommended daily intake.

Not intended for use by persona under 18. Keep out of reach of children.

Warning: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

Contains: Soy

Formulation Notes

Supports detoxification Supports liver health & detoxification pathways Powerful antioxidant Protection for the liver

No artificial colors or preservatives.

Additional Information

Store in a cool, dry place.

Available in fine health food stores everywhere

Metadata

Product Details

DSLD Entry Date2023-05-24
Product TypeBotanical with Nutrients
FormTablet or Pill
BrandNature's Secret
DSLD ID277722
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.