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Full Spectrum Milk Thistle Seed Extract

product on market Tablet or Pill Planetary Herbals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Milk thistle seed extract contains silymarin, which is researched for its potential to support liver function and protect hepatocytes. Evidence for these effects is generally considered moderate, though results vary across clinical studies. This ingredient profile maintains a high safety rating for most healthy adults.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Full Spectrum Milk Thistle Seed Extract
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
15
Servings
Botanical
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
200 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)

Other Ingredients

Sorbitol Stearic Acid modified Cellulose Gum Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: 2 to 4 tablets daily between meals.

Warnings & Precautions

Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Formulation Notes

Planetary Herbals Full Spectrum Milk Thistle Seed Extract is a highly concentrated extract of milk thistle seeds (Silybum marianum) that modern research has shown to support a healthy liver.

Extra milk thistle seeds are added to ensure the presence of important secondary compounds.

Additional Information

Supports healthy liver 260 mg

Approved by Michael Tierra L.Ac, O.M.D

This extract matches the constituent profile of extracts used in human research studies.

Store in a cool, dry place.

PF0363 REV A151

Metadata

Product Details

UPC / SKU0 21078 10363 9
DSLD Entry Date2017-07-25
Product TypeBotanical
FormTablet or Pill
DSLD ID75936
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.