🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

0.97 fl. Oz. Serving Size
1 Servings
Other Combinations Product Type
57% Evidence Coverage

Supplement Facts — Evidence Check

30 mg (188% DV)
✅ 2.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 30mg UL 35mg
40 mg (2353% DV)
📊 30.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 40mg UL 100mg
500 mcg (20833% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
2 mg (1% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 2mg UL 3500mg
Sodium
15 mg (1% DV)
Potassium
13 mg (1% DV)
Energy Blend
1870 mg

Other Ingredients

purified Water Natural and Artificial flavors Sucralose Potassium Sorbate Sodium Benzoate EDTA

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Kosher Women (not pregnant or lactating) Sugar Free

Product Information

📋 Directions for Use

Recommended Use: Take one half 1/2 bottle for moderate energy. Take one whole bottle for maximum energy. Do not exceed two bottles daily, consumed several hours apart. Use or discard any remainder within 72 hours (three days) after opening.

⚠️ Warnings & Precautions

Caution: Contains caffeine comparable to a cup of the leading premium coffee. Limit caffeine products to avoid nervousness, sleeplessness, and occasional rapid heartbeat. You may experience a Niacin Flush (hot feeling, skin redness) that lasts a few minutes. This is caused by increased blood flow near the skin.

Do not take if you are pregnant or nursing.

Not recommended for children.

If you are taking medication or have a medical condition, consult your doctor before use.

Phenylketonurics: Contains phenylalanine

🧪 Formulation Notes

Vitamins Nutrients Caffeine 4 Calories Grape flavor

Sugar free

Star K (Kosher)

Additional Information

Star K (Kosher)

Refrigeration not required.

Individual results may vary. See www.5hourenergy.com for more details.

Product Details

DSLD Entry Date 2022-09-22
Product Type Other Combinations
Form Liquid
DSLD ID 272145
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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