Prenatal Essentials by Doctor's Best — Ingredients, Evidence & Safety

🟢 92/100

This product looks safe

Folate: 600mg is 600.0× the Tolerable Upper Intake Level (1.0mg)
80% of ingredients have research evidence

C Label Compliance Grade

Product Label

📄 Open Full PDF View on NIH DSLD →

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Folate: 600mg is 600.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

4 Veggie Softgel(s) Serving Size

30 Servings

Other Combinations Product Type

80% Evidence Coverage

Supplement Facts — Evidence Check

Folate

600 mcg DFE (100% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 600.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 600mg UL 1.0mg

Vitamin B12

2.8 mcg (100% DV)

✅ 1.2× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.0028mg

Choline

550 mg (100% DV)

✅ Within RDA (1.0× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 550mg UL 3500mg

Iron

27 mg (100% DV)

DHA

250 mg

📊 Market median: 750.0mg (447 products) 📚 388 studies (Tier A: 18, B: 204)

This product: 250mg UL 3000mg

Other Ingredients

Food Starch - Modified Carrageenan Sorbitol Glycerin purified Water Red Iron Oxide Black Iron Oxide Sunflower Oil yellow Beeswax Sunflower Lecithin

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (77% of products) Nutrient (60% of products) Approved Health (5% of products)

Target Groups

Vegetarian Pregnant Women Adult Female (18 - 50 Years) Lactating Gluten Free

Product Information

📋 Directions for Use

Suggested Adult Use: Take 4 softgels with food or as directed by a nutritionally informed physician.

⚠️ Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In a case of accidental overdose, call a doctor or poison control center immediately.

🧪 Formulation Notes

This nurturing blend of Prenatal Essentials gives you the full recommended daily dose of choline (VitaCholine) to support fetal neural development. Choline helps increase the availability of DHA, which works together with folate (Quatrefolic) in its most bioavailable form to further support fetal brain & spinal development. Choline + B12 gives mom more energy. And for breastfeeding moms, continued choline supplementation will boost your bundle of joy's continued brain growth and development beyond pregnancy.

Supports A healthy prenatal regimen Fetal and neural development during pregnancy Breastfeeding moms for baby's continued brain development

Baby brain booster Essential nutrients for mother and baby

With Choline & DHA

Non-GMO Gluten free Soy free

Vegetarian

Additional Information

Store in a cool dry place.

Product Details

UPC / SKU 7 53950 00513 6

DSLD Entry Date 2022-06-16

Product Type Other Combinations

Form Softgel Capsule

Brand Doctor's Best

DSLD ID 271093

Data Updated 2026-04-11

Research Evidence

363 Research Sources

57 Avg Quality Score

187 Meta Analysis

56 Systematic Review

54 Rct

29 Guideline

26 Clinical Trial

6 Cochrane Review

2 Regulatory Source

1 Other

1 Openfda Safety

A Homocysteine-lowering interventions for preventing cardiovascular events

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI

A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI

A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies

Meta Analysis Digestive diseases and sciences 2021

PubMed DOI

A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis

Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021

PubMed DOI

A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Meta Analysis Nutrients 2024

PubMed DOI

A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis

Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025

PubMed DOI

A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies

Meta Analysis Critical reviews in food science and nutrition 2019

PubMed DOI

A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials

Meta Analysis Critical reviews in food science and nutrition 2022

PubMed DOI

A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants

Meta Analysis Critical reviews in food science and nutrition 2023

PubMed DOI

A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI

View all evidence for Folate →