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Glucosamine Chondroitin MSM + Hyaluronic Acid

product on market Capsule Doctor's Best Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Glucosamine and chondroitin sulfate are widely studied for supporting joint health, though research evidence for their efficacy remains moderate. Hyaluronic acid and MSM are often included to assist with joint lubrication and inflammation. Overall, these ingredients have a strong safety profile for most users.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Glucosamine Chondroitin MSM + Hyaluronic Acid
Open Full PDF View on NIH DSLD →
Details

Label Data

5 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

167 mg (7% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Sodium
95 mg (4% DV)
Potassium
170 mg (4% DV)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
MSM
1000 mg
Market median: 1000.0mg (2 products)
Market median: 20.0mg (931 products) 234 studies (A:1, B:90)

Other Ingredients

Gelatin Rice powder Magnesium Stearate Silicon Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Adult Use: Take 5 capsules daily with food, or as recommended by a nutritionally-informed physician.

Warnings & Precautions

Contains Shellfish (crab and shrimp shells)

Warning: Consult your physician before using any health supplement if pregnant, lactating, or have a medical condition.

Not for use by individuals under the age of 18 years. Keep out of reach of children.

Formulation Notes

Doctor's Best Glucosamine Chondroitin MSM + Hyaluronic Acid provides four important nutrients which help maintain healthy joints and connective tissues: glucosamine, chondroitin, Methylsulfonylmethane (MSM, from OptiMSM), and Hyaluronic Acid (from BioCell Collagen). Glucosamine sulfate and chondroitin sulfate help maintain healthy joints. MSM supplies bioavailable sulfur needed to support joint health, hair, skin, and nails. Hyaluronic acid plays an important role in the joint fluid cells, tissue hydrodynamics, and physiological functions, to support and maintain hydration, elasticity and microcirculation of healthy joints.

Helps support joint health Helps support and maintain tissue hydration Helps support healthy hair, skin and nails

With OptiMSM BioCell Collagen

Helps support healthy joints, hair, skin and nails

Non-GMO Gluten free Soy free

Additional Information

Store in a cool dry place.

Metadata

Product Details

UPC / SKU7 53950 00271 5
DSLD Entry Date2022-06-16
Product TypeOther Combinations
FormCapsule
BrandDoctor's Best
DSLD ID269587
Data Updated2026-04-11
Research

Research Evidence

14
Research Sources
50
Avg Quality
9
Rct
3
Clinical Trial
1
Systematic Review
1
Guideline
B Dressings and topical agents containing hyaluronic acid for chronic wound healing
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
B Effect of laughter exercise versus 0.1% sodium hyaluronic acid on ocular surface discomfort in dry eye disease: non-inferiority randomised controlled trial
Rct BMJ (Clinical research ed.) 2024 PubMed DOI
B Expert consensus on hyaluronic acid injections for knee osteoarthritis: a patient-centered approach.
Guideline Aging clinical and experimental research 2026 PubMed DOI
C The Effects of Dietary Supplementation with Collagen and Vitamin C and Their Combination with Hyaluronic Acid on Skin Density, Texture and Other Parameters: A Randomised, Double-Blind, Placebo-Controlled Trial
Rct Nutrients 2024 PubMed DOI
C Effects of ozone combined with articular injection of sodium hyaluronate on patients with knee osteoarthritis and their inflammatory factors and hemorheological indices.
Rct African health sciences PubMed DOI
C The effect of oral low molecular weight liquid hyaluronic acid combination with glucosamine and chondroitin on knee osteoarthritis patients with mild knee pain: An 8-week randomized double-blind placebo-controlled trial.
Rct Medicine PubMed DOI
C Liquid combination of hyaluronan, glucosamine, and chondroitin as a dietary supplement for knee osteoarthritis patients with moderate knee pain: A randomized controlled study.
Rct Medicine PubMed DOI
C Oral preparation of hyaluronic acid, chondroitin sulfate, N-acetylglucosamine, and vitamin C improves sexual and urinary symptoms in participants with recurrent urinary tract infections: a randomized crossover trial.
Rct The journal of sexual medicine PubMed DOI
C PMCF Study to Evaluate Performance and Safety of 'Hyaluronic Acid (HA)-Based Eyedrops' Used to Relieve Dry Eye Symptoms
Clinical Trial ClinicalTrials.gov 2022
C Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections
Clinical Trial ClinicalTrials.gov 2022
View all evidence for Hyaluronic Acid →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.