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Immune Defense Great Mixed Berry Flavor

product on market Tablet or Pill Culturelle Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Lactobacillus rhamnosus GG, Vitamin C, and Zinc are supported by strong evidence for maintaining immune function and gut health. These ingredients contribute to the body's natural defenses and cellular support. The overall profile is considered safe for general consumption.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Immune Defense Great Mixed Berry Flavor
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
28
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin C
90 mg (100% DV)
3 mg (27% DV)
Within RDA (0.3× RDA) 263 studies (A:6, B:134)
Market median: 80.0mg (20 products) 337 studies (A:8, B:183)
Market median: 175.0mg (497 products) 11 studies (A:0, B:1)

Other Ingredients

Mannitol Xylitol Hydroxypropyl Cellulose Stearic Acid Natural Flavors Magnesium Stearate Stevia leaf extract Vegetable Juice
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Once daily

Directions: Take one (1) tablet daily. Tablet may be chewed or swallowed as desired. Continued use is suggested.

Warnings & Precautions

Tamper Evident: Product is sealed within a vial. Do not use if any part of the vial is torn, open or damaged. When first taking Culturelle, you may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms persist after two weeks. For questions, concerns or to report an adverse event, please call (800) 722-3476.

Keep out of reach of children.

Inform a healthcare professional before starting any dietary supplement, particularly if there is a known immune-compromised condition.

Formulation Notes

Culturelle Immune Defense leverages a powerful blend containing clinically studied probiotics, along with naturally-sourced elderberry, plus vitamin C & zinc. It helps keep you feeling your best all year long. LGG Probiotic LGG strain is the most clinically studied probiotic & helps protect your immune health by working in your body’s digestive system where 70% of your immune system is located. Elderberry, Vitamin C & Zinc Made with real elderberry fruit, these chewables taste great and deliver zinc and the antioxidant vitamin C to help support your immune system.

Culturelle probiotics are great for a healthy microbiome & a healthy microbiome is great for a healthy you. Bilayer tablet

Not a reduced calorie food.

Naturally sourced LGG strain

Most clinically researched strain in the world Based on the number of scientific and clinical studies of Lactobacillus rhamnosus GG for a range of benefits as of January 2020. Guaranteed purity & potency Guaranteed potency through date on box when stored as directed.

Dairy Gluten While this product contains an ingredient sourced from wheat, it meets the FDA's definition of gluten free (less than 20 ppm gluten). Soy Free

Probiotics Super immunity chewables

Probiotic + Elderberry, Vitamin C & Zinc

Helps keep your immune system going strong Helps to keep you healthy

Great mixed berry flavor with other natural flavors

Allergy Friendly

Free from Tree nuts Peanuts Milk Eggs

Additional Information

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight.

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Our brand values We’re on a mission to inspire better health & wellness for you & your family. We believe in integrity, so we hold ourselves to the highest standards of truth. We believe in the natural power of your body’s microbiome, & in scientific research & products that will unlock its full potential. We believe in uncompromising quality, safety & proven efficacy. We believe in empowering you to embrace every day with confidence.

The Culturelle difference Excludes gummy formulas. From the Most Trusted Probiotic Brand Based on the 2019 BrandSpark American Shopper Study.

Metadata

Product Details

UPC / SKU0 49100 40122 5
DSLD Entry Date2022-06-16
Product TypeOther Combinations
FormTablet or Pill
DSLD ID268506
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.