🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Chewable Tablet(s) Serving Size
20 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calories
Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin C
90 mg (600% DV)
1.88 mg (63% DV)
✅ Within RDA (0.2× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 1.88mg UL 40mg
📊 Market median: 80.0mg (20 products) 📚 334 studies (Tier A: 8, B: 183)
This product: 26mg
📊 Market median: 175.0mg (497 products) 📚 11 studies (Tier A: 0, B: 1)
This product: 50mg

Other Ingredients

Xylitol Mannitol Hydroxypropyl Cellulose Stearic Acid Natural Flavors Magnesium Stearate Vegetable Juice Stevia leaf extract

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Children 4 or More Years of Age Gluten Free Dairy Free Children more than 1 but less than 4

Product Information

📋 Directions for Use

Directions for children 3-12 years: Take one (1) chewable tablet at any time of day with or without food. For ongoing digestive and immune support, continued daily use is recommended.

⚠️ Warnings & Precautions

Tamper Evident: Product is sealed within a vial. Do not use if any part of the vial is torn, open or damaged. When first taking Culturelle, your child may experience minor bloating, gas or intestinal gurgling which should subside with continued use. Consult your healthcare professional if symptoms persist after two weeks. For questions, concerns or to report an adverse event, please call (800) 722-3476.

Keep out of reach of children. Not intended for children under 3 years of age due to risk of choking.

Inform a healthcare professional before starting any dietary supplement, particularly if there is a known immune-compromised condition

🧪 Formulation Notes

Culturelle Kids Immune Defense leverages a powerful blend containing scientifically proven probiotics, along with naturally-sourced elderberry, plus vitamin C & zinc.

It helps keep your little ones feeling their best all year long.

LGG Probiotic LGG strain is the most scientifically studied probiotic in children & helps protect their immune health by activating the power of their microbiome. Elderberry, Vitamin C & Zinc Made with real elderberry fruit, these chewables taste great & deliver zinc & the antioxidant vitamin C to help support your child’s immune system.

Bilayer tablet

Based on the number of scientific and clinical studies of Lactobacillus rhamnosus GG for a range of benefits as of January 2020.

Guaranteed potency through date on box when stored as directed.

While this product contains an ingredient sourced from wheat, it meets the FDA’s definition of gluten free (less than 20 ppm gluten).

Naturally sourced LGG

Most clinically researched strain in the world Guaranteed purity & potency

Dairy, Gluten, Soy Free

Probiotics

Probiotic + Elderberry, Vitamin C & Zinc

Super immunity chewables Promotes immune & upper respiratory health Helps keep your kids healthy & strong

Mixed berry flavor chewable tablets with other natural flavors

Allergy Friendly

Allergy Friendly Free from Tree Nuts, Peanuts, Milk, Eggs

Not a reduced calorie food.

Additional Information

Storage Instructions: Store Culturelle in a cool, dry place away from direct sunlight.

Scan to learn more

Based on a 2020 survey among pediatricians recommending a probiotic brand.

Our brand values We’re on a mission to inspire better health & wellness for you & your family. We believe in integrity, so we hold ourselves to the highest standards of truth. We believe in the natural power of your body’s microbiome, & in scientific research & products that will unlock its full potential. We believe in uncompromising quality, safety & proven efficacy. We believe in empowering you to embrace every day with confidence.

The Culturelle difference

From the #1 Pediatrician Recommended Brand

Excludes gummy formulas

Product Details

UPC / SKU 0 49100 40126 3
DSLD Entry Date 2022-06-16
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 267603
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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