GuggulXtra by DC — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

⚠️ Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)

Label Data

1 Capsule(s) Serving Size

90 Servings

Botanical with Nutrients Product Type

50% Evidence Coverage

Supplement Facts — Evidence Check

Niacin

125 mg NE (781% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 3.6× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 125mg UL 35mg

Calcium

26.88 mg (2% DV)

Chromium

25 mcg (71% DV)

✅ Within RDA (0.7× RDA of 0.035 mg) 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.025mg

Potassium

11 mg (1% DV)

Gugul extract

125 mg

Ginger root extract

100 mg

📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)

This product: 100mg

Other Ingredients

Vegetable Cellulose Gelatin Vegetable Magnesium Stearate

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take 1 capsule three times daily.

⚠️ Warnings & Precautions

Tamper Evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing do not take this product.

🧪 Formulation Notes

FDA Registered Facility (Reg. #1023013) Mfg. under Good Manufacturing Practices (GMPs) Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

ChromeMate

Made in USA

Gluten free

Standardized 2.5% gugulsterones

Helps maintain cholesterol levels that are already within normal range

Additional Information

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees to 30 degrees C).

Quali Pure

Product Details

DSLD Entry Date 2022-04-11

Product Type Botanical with Nutrients

Form Capsule

Brand DC

DSLD ID 265835

Data Updated 2026-04-11

Research Evidence

241 Research Sources

55 Avg Quality Score

113 Meta Analysis

75 Systematic Review

32 Rct

11 Clinical Trial

3 Other

3 Regulatory Source

1 Cochrane Review

1 Narrative Review

1 Openfda Safety

A Niacin for primary and secondary prevention of cardiovascular events

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases

Meta Analysis BMJ (Clinical research ed.) 2013

PubMed DOI

A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients

Meta Analysis BMJ (Clinical research ed.) 2014

PubMed DOI

A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk

Meta Analysis Nature medicine 2024

PubMed DOI

A Meta-analysis and imputation refines the association of 15q25 with smoking quantity

Meta Analysis Nature genetics 2010

PubMed DOI

A Genome-wide meta-analyses identify multiple loci associated with smoking behavior

Meta Analysis Nature genetics 2010

PubMed DOI

A Antidepressants for smoking cessation

Meta Analysis The Cochrane database of systematic reviews 2014

PubMed DOI

A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI Cochrane

B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis

Meta Analysis JAMA network open 2019

PubMed DOI

B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis

Meta Analysis JAMA 2016

PubMed DOI

View all evidence for Niacin →