🟢 87/100

This product is generally safe

  • Nicotinamide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Nicotinamide: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label Data

1 Vegetable Capsule(s) Serving Size
120 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

500 mg (3125% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 500mg UL 35mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 100mg UL 1200mg
Black Pepper extract
5 mg

Other Ingredients

Vegetable Cellulose Rice Flour

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take one (1) capsule daily. For best results, take with a meal or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Caution: Do not exceed the recommended dose.

Not intended for pregnant or nursing mothers.

Not intended for children under 18 years of age.

If you are taking any medications, have a known medical condition, or are planning a medical procedure, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Non-GMO formula High quality supplement Flush free High quality supplement

With CoQ10

Promotes cellular health & repair Supports immunity & brain health Supports energy production

Vegan friendly

aSquared Nutrition is proud to offer a maximum strength Nicotinamide supplement enhanced with CoQ10 to promote cellular health, support immunity & brain health, and to help boost energy production. Our formula contains 500 mg of Nicotinamide and 100 mg of CoQ10 powder in each capsule.

Additional Information

GMP Good Manufacturing Practice Quality Assured

Please recycle.

Store in a cool, dry place.

USA Formulated

Product Details

UPC / SKU X002HEUIO1
DSLD Entry Date 2022-04-11
Product Type Other Combinations
Form Capsule
DSLD ID 263982
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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