🟢 96/100

This product looks safe

  • Vitamin B3: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Vitamin B3: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label Data

6 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
67% Evidence Coverage

Supplement Facts — Evidence Check

200 IU (667% DV)
📊 8.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 134.0mg UL 1000mg
100 mg (500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 100mg UL 35mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 500mg
300 mg (3000% DV)
📊 60.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 300mg
400 mcg (333% DV)
📊 11.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.4mg
2000 mg
📊 Market median: 1000.0mg (223 products) 📚 11 studies (Tier A: 0, B: 5)
This product: 2000mg
Pantethine
500 mg
Chlorophyll
300 mg
5 mg
📊 Market median: 500.0mg (497 products) 📚 132 studies (Tier A: 0, B: 40)
This product: 5mg

Other Ingredients

Silica Vegetable Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (98% of products) Structure/Function (81% of products) Nutrient (56% of products) Qualified Health (2% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested use for adults: Six tablets daily in divided doses, or as directed by your health care practitioner. Supplementation of CoQ-10 is recommended, as red yeast rice components may lower tissue levels of CoQ-10.

⚠️ Warnings & Precautions

Keep out of reach of children.

🧪 Formulation Notes

Natural cholesterol and lipid metabolism modifiers

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

This product contains no wheat, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

Keep in a cool, dry place, tightly capped.

Product Details

UPC / SKU 0 18647 09127 5
DSLD Entry Date 2022-06-16
Product Type Other Combinations
Form Capsule
Brand Karuna
DSLD ID 262717
Data Updated 2026-04-11

Research Evidence

253 Research Sources
55 Avg Quality Score
128 Meta Analysis
52 Systematic Review
41 Rct
24 Clinical Trial
3 Regulatory Source
1 Narrative Review
1 Other
1 Guideline
1 Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022
View all evidence for Vitamin E →

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