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L-Tryptophan 500 mg

product on market Capsule Advanced Nutrition by Zahler Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

L-tryptophan is an essential amino acid used as a precursor for serotonin and melatonin, while Vitamin B3 supports cellular metabolism. There is moderate research evidence supporting their roles in mood regulation and energy production. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for L-Tryptophan 500 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Amino acid/Protein
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

8.3 mg (52% DV)
Within RDA (0.6× RDA) 196 studies (A:5, B:63)
500 mg
Market median: 500.0mg (70 products)

Other Ingredients

Cellulose Magnesium Stearate Rice Flour
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 1 capsule daily, preferably without food, or as directed by a healthcare practitioner.

Warnings & Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

If pregnant, nursing or on medication, consult with your healthcare practitioner.

Formulation Notes

High potency serotonin enhancer

L-Tryptophan is used by the brain as a precursor to serotonin and melatonin, neurotransmitters that are necessary for normal sleep. Adequate sleep is crucial for healthy immune and nervous system function. In addition, changes in the level of serotonin in the brain can impact mood and satiety.

Kosher Pareve Under the strict supervision of Rabbi SH. Stern & the orthodox union

Non-GMO Gluten free Dairy free Soy free

Vegetarian friendly

Purified L-Tryptophan

High Potency Serotonin Enhancer Mind & spirit

500 mg per serving

Additional Information

You may need additional supplements to support a healthy diet; consult your nutritionist for a formula that is right for you or contact us at 877-ASK-ZAHLER (877-275-9245) or ask@zahlers.com.

Dairy (Kosher) OU (Kosher) This product was manufactured in a GMP certified Facility

Store tightly closed in a cool, dry place.

Made in the USA

Metadata

Product Details

UPC / SKU8 48998 08124 9
DSLD Entry Date2022-04-11
Product TypeAmino acid/Protein
FormCapsule
DSLD ID260163
Data Updated2026-04-11
Research

Research Evidence

29
Research Sources
48
Avg Quality
19
Rct
5
Meta Analysis
3
Systematic Review
2
Clinical Trial
B Prebiotic and probiotic supplementation and the tryptophan-kynurenine pathway: A systematic review and meta analysis
Meta Analysis Neuroscience and biobehavioral reviews 2021 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression
Meta Analysis Nutrition reviews 2022 PubMed DOI
B No effects of acute tryptophan depletion on anxiety or mood in weight-recovered female patients with anorexia nervosa
Rct European archives of psychiatry and clinical neuroscience 2023 PubMed DOI
C The association between tryptophan levels and postpartum mood disorders: a systematic review and meta-analysis
Meta Analysis BMC psychiatry 2022 PubMed DOI
C A systematic review of the effect of L-tryptophan supplementation on mood and emotional functioning
Systematic Review Journal of dietary supplements 2021 PubMed DOI
C Comparison between Acupuncture and Nutraceutical Treatment with Migratens® in Patients with Fibromyalgia Syndrome: A Prospective Randomized Clinical Trial.
Rct Nutrients PubMed DOI
C Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study.
Rct Nutrients PubMed DOI
C Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis
Meta Analysis The Australian and New Zealand journal of psychiatry 2002 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.