🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 36% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

18 Gram(s) Serving Size
25 Servings
Other Combinations Product Type
36% Evidence Coverage

Supplement Facts — Evidence Check

40 mg (7% DV)
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 40mg UL 3500mg
4000 mg
📊 Market median: 2000.0mg (275 products)
Median 2000.0mg This product: 4000mg
3200 mg
📊 Market median: 1500.0mg (104 products) 📚 21 studies (Tier A: 0, B: 2)
This product: 3200mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 2000mg
Agmatine Sulfate
1500 mg
1500 mg
📊 Market median: 500.0mg (223 products) 📚 22 studies (Tier A: 0, B: 1)
This product: 1500mg
📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)
This product: 400mg UL 400mg
N-Palmitoylethanolamide
300 mg
Theobromine
200 mg
✅ Within RDA (0.2× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 100mg UL 3500mg
DMAE
100 mg
Black Pepper extract
5 mg
Rauwolfia vomitoria extract
3 mg
📊 Market median: 0.15mg (41 products)
Median 0.15mg This product: 2mg

Other Ingredients

Malic Acid Natural and Artificial flavor Silica Calcium Silicate Sucralose Acesulfame Potassium

Label Claims — Verification

No Claim
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

🧪 Formulation Notes

Naturally & Artificially flavored powder

Product Details

DSLD Entry Date 2021-09-24
Product Type Other Combinations
Form Powder
DSLD ID 257774
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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