RepleteExtra
87/100
This product is generally safe
- Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
- 100% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
4 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Supplement Facts — Evidence Check
680 mcg DFE
(170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
1000 mg
📊 Market median: 500.0mg (223 products)
📚 22 studies (Tier A: 0, B: 1)
300 mg
📊 Market median: 100.0mg (116 products)
📚 15 studies (Tier A: 0, B: 3)
Other Ingredients
Vegetable Capsule
Rice Flour
Cellulose
Silicon Dioxide
Magnesium Stearate
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (77% of products)
Nutrient (60% of products)
Approved Health (5% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Directions: Take 4 capsules once or twice a day or as directed by your healthcare practitioner. Use only under medical supervision.
Use of CysReplete is recommended with this product to prevent sulfur amino acid depletion.
⚠️ Warnings & Precautions
If you are pregnant or nursing consult your health care practitioner before use.
Keep away from children
🧪 Formulation Notes
98% + Pure 5-HTP
Does not contain wheat, corn, soy, sucrose, salt, starch, yeast, artificial flavors, artificial colorings, or other known allergens.
This product is manufactured in a cGMP certified facility.
GF Gluten-free
Additional Information
This product is intended for resale.
Keep away from direct sunlight
Product Details
DSLD Entry Date
2021-08-23
Product Type
Other Combinations
Form
Capsule
Brand
CHK Nutrition
DSLD ID
252904
Data Updated
2026-04-11
Research Evidence
363
Research Sources
57
Avg Quality Score
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A
Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
A
Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
A
The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
A
A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A
Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
A
Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
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