7-Keto DHEA Metabolite 100 mg by Life Extension — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

⚠️ 7-Keto DHEA: 100mg is 2.0× the Tolerable Upper Intake Level (50mg)

Label Data

1 Vegetarian Capsule(s) Serving Size

Other Combinations Product Type

57% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C

10 mg (17% DV)

Vitamin E

25 IU (83% DV)

✅ 1.1× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 16.75mg UL 1000mg

7-Keto DHEA

100 mg

⚠️ Exceeds Tolerable Upper Intake Level by 2.0× (UL: 50 mg) 📚 17 studies — no high-quality reviews

This product: 100mg UL 50mg

Ascorbyl Palmitate

25 mg

Turmeric extract

25 mg

📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)

This product: 25mg

Green tea extract, decaffeinated

25 mg

📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)

This product: 25mg

Whole grape extract (Vitis vinifera) and Polygonum cuspidatum (root) extract

3 mg

📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)

This product: 3mg

Other Ingredients

Rice Flour Cellulose Magnesium Stearate

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (72% of products) Nutrient (2% of products)

Target Groups

Vegetarian Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Take one (1) capsule upon waking and one (1) capsule before midday meal, preferably on an empty stomach, or as recommended by a healthcare practitioner.

⚠️ Warnings & Precautions

WARNINGS: - KEEP OUT OF REACH OF CHILDREN.

- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

Contains rice.

- DO NOT EXCEED RECOMMENDED DOSE.

- Do not purchase if outer seal is broken or damaged.

🧪 Formulation Notes

Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, or corn.

Additional Information

Store tightly closed in a cool, dry place.

01271B Rev. 6/09

For optimal potency use by: Lot No.:

Natural Metabolite of DHEA

Read the entire label and follow the directions carefully prior to use.

Product Details

UPC / SKU 7 37870 12716 1

DSLD Entry Date 2011-11-25

Product Type Other Combinations

Form Capsule

Brand Life Extension

DSLD ID 2502

Data Updated 2026-04-11

Research Evidence

30 Research Sources

49 Avg Quality Score

21 Rct

5 Meta Analysis

2 Systematic Review

1 Other

1 Guideline

A Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI Cochrane

B Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B The auxiliary effect of oral nutritional supplements on fertility in women with diminished ovarian reserve: a systematic review and meta-analysis

Meta Analysis Annals of medicine 2025

PubMed DOI

B Impact of dehydroepiandrosterone (DHEA) supplementation on testosterone concentrations and BMI in elderly women: A meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2021

PubMed DOI

B Supplementation of dehydroepiandrosterone (DHEA) in pre- and postmenopausal women - position statement of expert panel of Polish Menopause and Andropause Society.

Guideline Ginekologia polska 2020

PubMed DOI

B Effect of Dehydroepiandrosterone and Testosterone Supplementation on Systemic Lipolysis

Rct The Journal of clinical endocrinology and metabolism 2016

PubMed DOI

C Impact of growth hormone and dehydroepiandrosterone on protein metabolism in glucocorticoid-treated patients

Rct The Journal of clinical endocrinology and metabolism 2008

PubMed DOI

C Associations between blood sex steroid concentrations and risk of major adverse cardiovascular events in healthy older women in Australia: a prospective cohort substudy of the ASPREE trial.

Rct The lancet. Healthy longevity

PubMed DOI

C Peculiar observations in measuring testosterone in women treated with oral contraceptives supplemented with dehydroepiandrosterone (DHEA)

Rct Clinica chimica acta; international journal of clinical chemistry 2014

PubMed DOI

C Dehydroepiandrosterone improves psychological well-being in male and female hypopituitary patients on maintenance growth hormone replacement

Rct The Journal of clinical endocrinology and metabolism 2006

PubMed

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