🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Caplique Capsule(s) Serving Size
30 Servings
Non-Nutrient/Non-Botanical Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

400 mg
✅ Within RDA (0.7× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 400mg UL 3500mg

Other Ingredients

Glycerin Vegetarian Caplique (symbols) Capsule Water

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommendations: As a dietary supplement, take 2 caplique capsules, 3 times daily, with or between meals.

⚠️ Warnings & Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Keep out of the reach of children.

Use only if safety seal is intact.

Contains soy

🧪 Formulation Notes

Gluten-free & Non-GMO

Each Caplique Capsule is preserved with a nitrogen bubble, with may give the appearance of the capsule not being full. Contents may appear cloudy or thick and may settle or separate.

Additional Information

Store in a cool, dry place.

Scan to learn about our hypoallergenic supplements Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Neurotransmitter and phospholipid precursor: Supports cognitive health

Product Details

UPC / SKU 7 66298 01594 1
DSLD Entry Date 2021-03-25
Product Type Non-Nutrient/Non-Botanical
Form Capsule
DSLD ID 245975
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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