🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 29% of ingredients have research evidence
B Label Compliance Grade

Product Label

📸

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Label Data

2 Tablet(s) Serving Size
60 Servings
Other Combinations Product Type
29% Evidence Coverage

Supplement Facts — Evidence Check

Fumitory
250 mg
200 mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 200mg
200 mg
📊 Market median: 500.0mg (234 products) 📚 95 studies (Tier A: 0, B: 35)
This product: 200mg
Artichoke leaf extract
200 mg
250 mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 250mg
200 mg
📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 200mg
200 mg
📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews
This product: 200mg

Other Ingredients

Magnesium Stearate Stearic Acid Silicon Dioxide Cellulose Dicalcium Phosphate

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested use for adults: Two tablets twice daily, away from meals, or as directed by your health care practitioner.

🧪 Formulation Notes

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

9109-LB4

KARUNA(R) RESPONSIBLE NUTRITION(TM)

Herbal and Lipotropic Complex

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place, tightly capped.

EXP11/2012 LOT9J724-0

Product Details

DSLD Entry Date 2013-08-23
Product Type Other Combinations
Form Tablet or Pill
Brand Karuna
DSLD ID 24419
Data Updated 2026-04-11

Research Evidence

69 Research Sources
55 Avg Quality Score
34 Meta Analysis
26 Systematic Review
5 Rct
3 Clinical Trial
1 Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024
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