Methylation Support
92/100
This product looks safe
- Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
- 80% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
3 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
80%
Evidence Coverage
Supplement Facts — Evidence Check
50 mg
(2941% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
667 mcg DFE
(167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
800 mcg
(33333% DV)
📊 333.3× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
75 mg
(14% DV)
✅ Within RDA (0.1× RDA of 550 mg)
📚 36 studies (Tier A: 1, B: 7)
1500 mg
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
Other Ingredients
Hypromellose
Hyprolose
Sunflower Lecithin
Silica
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (98% of products)
Structure/Function (89% of products)
Nutrient (43% of products)
Target Groups
Adult (18 - 50 Years)
Product Information
📋 Directions for Use
Recommended Dose: Take 3 capsules daily or as recommended by your health professional.
⚠️ Warnings & Precautions
Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your healthcare professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
🧪 Formulation Notes
Supports healthy homocysteine metabolism
Additional Information
Store in a cool, dry place.
Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our quality excellence
Product Details
UPC / SKU
8 83196 14680 2
DSLD Entry Date
2020-11-21
Product Type
Other Combinations
Form
Capsule
Brand
Genestra Brands
DSLD ID
239080
Data Updated
2026-04-11
Research Evidence
153
Research Sources
55
Avg Quality Score
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A
Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
A
Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
B
Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
B
The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
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