SAMe
100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- Limited research evidence available for ingredients
B
Label Compliance Grade
Product Label
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Label Data
1 Tablet(s)
Serving Size
10
Servings
Non-Nutrient/Non-Botanical
Product Type
0%
Evidence Coverage
Supplement Facts — Evidence Check
400 mg
📊 Market median: 500.0mg (193 products)
📚 7 studies — no high-quality reviews
Other Ingredients
Cellulose
Mannitol
Methacrylic Acid Copolymer
Citric Acid
Stearic Acid
Silica
Titanium Dioxide
Hydroxypropyl Methylcellulose
Glyceryl Triacetate
Sodium Starch Glycolate
Croscarmellose Sodium
yellow Ochre
Label Claims — Verification
❓
All Other
All Other (100% of products)
Structure/Function (83% of products)
Nutrient (6% of products)
Target Groups
Adult (18 - 50 Years)
Product Information
📋 Directions for Use
SAMe may be taken with Item #52580 Homocysteine Plus and/or Item #53230 TMG (Trimethylglycine).
Suggested Use As a dietary supplement, 1 or 2 tablets one to three times daily between meals, or as directed by a healthcare practitioner.
🧪 Formulation Notes
SAMe, a natural form of bioactive methionine, in enteric-coated tablets.
(S-Adenosylmethionine) Bioactive Methionine
Hypoallergenic
Additional Information
Keep in a cool, dry place, tightly capped.
NutriCology Innovative Nutrition
Product Details
UPC / SKU
7 13947 53190 1
DSLD Entry Date
2020-09-25
Product Type
Non-Nutrient/Non-Botanical
Form
Tablet or Pill
Brand
NutriCology
DSLD ID
235365
Data Updated
2026-04-11
Research Evidence
12
Research Sources
58
Avg Quality Score
8
Meta Analysis
3
Systematic Review
1
Rct
B
S-adenosyl-L-methionine for alcoholic liver diseases
B
S-adenosyl methionine (SAMe) for depression in adults
B
Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease
B
SAMe-TT2R2 Score to Predict Time in Therapeutic Range of Vitamin K Antagonists in Asian and Non-Asian patients: A Systematic Review and Meta-analysis
B
S-Adenosylmethionine (SAMe) as an adjuvant therapy for patients with depression: An updated systematic review and meta-analysis
B
S-adenosyl-L-methionine for alcoholic liver diseases
C
S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis
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