Home/ Supplements/ Betaine/ Betaine Anhydrous (TMG) Endurance 450 mg

Betaine Anhydrous (TMG) Endurance 450 mg

product on market Capsule Chief Originals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • Limited research evidence available for ingredients
B Label Compliance Grade
Label

Product Label

Label for Betaine Anhydrous (TMG) Endurance 450 mg
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Non-Nutrient/Non-Botanical
Product Type
0%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 496.0mg (192 products) 20 studies — no high-quality reviews

Other Ingredients

Betaine Anhydrous Vegetarian Capsules
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Warnings & Precautions

Manufactured in a facility which may contain nuts (peanuts, tree nuts).

If pregnant or under a doctor’s care, consult your physician before using this product.

Do not use if the safety seal is broken.

Keep out of reach of children.

Formulation Notes

Chief Originals Betaine Anhydrous (TMG), also called trimethylglycine, is a nutrient derived from non-GMO beet root. Betaine Anhydrous has an assortment of supportive functions for human health.

Non GMO Gluten free

No pesticide

Lab verified Chine free

Betaine Anhydrous (TMG) 900 mg per day formula

Soy-free

Additional Information

1% of proceeds donated to Native American causes

Low Heavy Metals Verified

Product of Finland

Metadata

Product Details

UPC / SKU0 50742 58205 0
DSLD Entry Date2020-06-24
Product TypeNon-Nutrient/Non-Botanical
FormCapsule
BrandChief Originals
DSLD ID229126
Data Updated2026-04-11
Research

Research Evidence

23
Research Sources
47
Avg Quality
18
Rct
3
Systematic Review
1
Meta Analysis
1
Clinical Trial
B Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
Rct Nutrients 2016 PubMed DOI
C Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
Rct Hepatology (Baltimore, Md.) 2009 PubMed DOI
C Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
Systematic Review Journal of inherited metabolic disease 2017 PubMed DOI
C Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
Systematic Review Journal of inherited metabolic disease 2015 PubMed DOI
C Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
Rct European journal of nutrition 2023 PubMed DOI
C Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
Meta Analysis International orthodontics 2019 PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition PubMed DOI
C Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
Rct Clinical nutrition ESPEN PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition PubMed DOI
C Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine
Rct Cardiovascular drugs and therapy 2009 PubMed DOI
View all evidence for Betaine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.