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DB12 Digestives + Vitamin B12

product on market Capsule Systemic Formulas Bio Function Safety: 90/100
90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 71% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B-vitamins and folic acid, which are supported by strong evidence for supporting cellular energy metabolism and neurological function. Calcium is included to support skeletal and muscular health. Overall evidence coverage for this specific combination is limited, though the individual components maintain a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for DB12 Digestives + Vitamin B12
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
Other Combinations
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

30 mg (150% DV)
2.1× RDA — within safe limits 196 studies (A:5, B:63)
1 mg (68% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
18 mg (180% DV)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Calcium
6.5 mg
700 mcg (175% DV)
1.7× RDA — within safe limits 226 studies (A:10, B:105)
50 mcg (17% DV)
1.7× RDA — within safe limits 27 studies (A:0, B:11)
Proprietary Blend
500 mg

Other Ingredients

Gelatin Leucine
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS FOR NUTRITIONAL USE: 1capsule up to 3x daily with food or as directed. Increase the amount of liquids you drink each day while taking this product.

Warnings & Precautions

May cause niacin flush (a hot tingling effect to the skin) that may last 1-2 hours.

Keep away from Heat, Sunlight and Children.

Additional Information

Keep away from Heat, Sunlight and Children.

#19

Digestive enzymes with Betain HCl and vitamins to support healthy stomach digestion and the uptake of Vitamin B12 and other nutrients.

SOLD THROUGH PROFESSIONALS

MADE IN U.S.A.

G/12

Metadata

Product Details

UPC / SKU6 35585 00191 5
DSLD Entry Date2013-05-24
Product TypeOther Combinations
FormCapsule
BrandSystemic Formulas Bio Function
DSLD ID21847
Data Updated2026-04-11
Research

Research Evidence

237
Research Sources
53
Avg Quality
83
Meta Analysis
74
Systematic Review
45
Rct
29
Clinical Trial
2
Guideline
2
Regulatory Source
1
Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021 PubMed DOI
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024 PubMed DOI
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020 PubMed DOI
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024 PubMed DOI
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024 PubMed DOI
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023 PubMed DOI
View all evidence for Vitamin B12 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.