🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 43% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
43% Evidence Coverage

Supplement Facts — Evidence Check

20 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
2 mg (100% DV)
✅ 1.5× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 2mg UL 100mg
15 mg (150% DV)
✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 15mg
5 mg (250% DV)
✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 5mg UL 11mg
500 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 500mg
MSM
30 mg
📊 Market median: 1000.0mg (2 products)
This product: 30mg
Sugar Cane extract
25 mg

Other Ingredients

Gelatin Water Glycerin Cellulose Magnesium Stearate

Label Claims — Verification

Nutrient
All Other
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

RECOMMENDATION: One (1) capsule two (2) to three (3) times daily as a dietary supplement or as otherwise directed by a healthcare professional.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN

Sealed with an imprinted safety seal for your protection.

🧪 Formulation Notes

Contains ingredients derived from shrimp and crab shell.

Additional Information

Store in a cool, dry area.

Rev. 11/08

MSM is an excellent source of sulfur (about 1/3 by weight). Saccarum officinarum extract is a botanical source of silicon-far superior to Horsetail.

Lot Number: 34262a Exp. Date: FEB 12

Product Details

DSLD Entry Date 2013-05-24
Product Type Other Combinations
Form Capsule
DSLD ID 21824
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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