🟢 96/100

This product looks safe

  • Zinc: 69.6mg is 1.7× the Tolerable Upper Intake Level (40mg)
  • 33% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Zinc: 69.6mg is 1.7× the Tolerable Upper Intake Level (40mg)

Label Data

1 Softgel(s) Serving Size
60 Servings
Multi-Vitamin and Mineral (MVM) Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Fat
0.5 Gram(s) (0.6% DV)
Total Carbohydrates
0.5 Gram(s) (1% DV)
Protein
0.2 Gram(s) (1% DV)
Vitamin A
14320 IU (286% DV)
Vitamin C
452 mg (753% DV)
200 IU (667% DV)
📊 8.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 134.0mg UL 1000mg
69.6 mg (464% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.7× (UL: 40 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 69.6mg UL 40mg
1.6 mg (80% DV)
✅ 1.8× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 1.6mg UL 10mg

Other Ingredients

Gelatin Glycerin Soybean Oil Coconut Oil Corn Oil Lecithin Vegetable Glycerides Beeswax Polyunsaturated Oils Caramel Titanium Dioxide FD&C Red #40 Lake Oxalic Acid Metal Salts DL-Alpha-Tocopherol FD&C Yellow #6 Lake Cuprous Oxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

2 softgels per day

Suggested Adult Intake: Two Softgels per day; 1 in the morning and 1 in the evening with meals or as directed by your physician.

⚠️ Warnings & Precautions

Specific lifestyle considerations such as smoking should be considered when choosing the proper Systane ICaps formulation. Do not use if the safety seal under the cap is broken or missing. Caution: Softgels should be consumed whole. Do not consume damaged Softgels.

Keep out of reach of children.

Food supplementation should not be used as a substitute for a varied diet.

🧪 Formulation Notes

Lactose free

Systane ICaps Eye Vitamin & Mineral Supplement AREDS formula contains the same antioxidant and zinc levels used in the National Eye Institute's Age-Related Eye Disease Study (AREDS). AREDS is a ground-breaking, 10-year clinical study that proved the benefit of these high-potency antioxidant and zinc ingredients in certain patients at risk. It is important to note that the high-potency Vitamin C, Vitamin E and Zinc ingredient levels found in Systane ICaps Eye Vitamin AREDS formula generally can be obtained only by supplementation and not through diet alone.

Additional Information

Age-Related Eye Disease Study Helps Preserve Healthy Vision

Contains 120 Softgels

Systane ICaps Eye Vitamin & Mineral Supplement AREDS formula is developed by alcon, the world-wide leader in eye care. Each Systane ICaps Eye Vitamin AREDS formula Softgel is made of high quality ingredients and meets the rigorous quality-control standards of Alcon. Alcon is involved in research studying the potential positive effects of antioxidants and other ingredients on preserving healthy vision.

Keep tightly closed in a dry place at controlled room temperature.

The antioxidant and zinc ingredients used in the Age-Related Eye Disease Study (AREDS)

Developed by Alcon, the global leader in eye care products. Age-Related Eye Disease Study Research Group, Archives of Ophthalmology, 2001; 119:1417-1436

Product Details

DSLD Entry Date 2019-09-24
Product Type Multi-Vitamin and Mineral (MVM)
Form Softgel Capsule
Brand Alcon
DSLD ID 206649
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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