Home/ Supplements/ Thiamine/ Calm Nature

Calm Nature

product on market Capsule HoltraCeuticals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 7% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Thiamine and magnesium are well-studied nutrients that support neurological function and muscle relaxation. Dong quai is traditionally used for hormonal balance, though clinical evidence for its efficacy remains limited. Overall, the evidence coverage for this specific ingredient profile is very low.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Calm Nature
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
7%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

16 mg (1077% DV)
13.3× RDA — above typical dose 76 studies (A:0, B:33)
16 mg (4% DV)
Market median: 500.0mg (1 products) 316 studies (A:8, B:159)
Calm Nature
1462 mg
Calm Nature:
Dong quai
Poria
codonopsis
Jujube Fruit Extract
Mimosa Tree
European Peony
biota
fo-ti extract
dwarf morning glory root extract
plant enzymes
bupleurum extract
lily turf
ligusticum extract
Passion Flower extract
Chinese peony flower extract
2000 GDU
Market median: 200.0mg (136 products) 3 studies — no high-quality reviews
Papain
40000 FCC

Other Ingredients

Rice Bran Gelatin
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Use: 3 capsules per day or as directed by your physician.

Warnings & Precautions

Keep out of reach of children.

If you are under medical supervision seek the advice of your qualified healthcare provider prior to use of this product.

Pregnant or lactating women should consult their qualified healthcare provider prior to use.

Additional Information

Store in a cool, dry place protected from light.

*Promotes Relaxation and Emotional Balance

Metadata

Product Details

DSLD Entry Date2013-03-25
Product TypeOther Combinations
FormCapsule
BrandHoltraCeuticals
DSLD ID19335
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
Compare

Similar Products

Bio-Cetin Forte
Douglas Laboratories · Capsule
100
Benfotiamine-V 150 mg
Benfotiamine.Net · Capsule
100
Vitamin B1 250 mg
The Vitamin Shoppe · Capsule
100
Vitamin B1 250 mg
The Vitamin Shoppe · Capsule
100
Vitamin B1 (Thiamin) 100 mg
Solgar · Capsule
100
View all Thiamine products →
Thiamine research Best Thiamine All Thiamine products More from HoltraCeuticals View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.