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Adrenal-Calm

product on market Capsule HoltraCeuticals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains adaptogens like Ashwagandha, Rhodiola, and Eleuthero, which have moderate evidence for supporting stress responses and cognitive function. L-Theanine and Skullcap are included for their researched effects on relaxation and anxiety reduction. Overall, clinical evidence for these combined ingredients is limited due to low specific product coverage.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Adrenal-Calm
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Ashwaganda root extract
250 mg
Skullcap root extract
250 mg
Market median: 450.0mg (390 products) 160 studies (A:0, B:63)
Market median: 300.0mg (122 products) 22 studies (A:0, B:7)
100 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)
Market median: 100.0mg (108 products)

Other Ingredients

natural Vegetable Capsules This product may contain one or more of the following:
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

SUGGESTED USE: 2 capsules 1-2 times per day or as recommended by your health care professional.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

This product was sealed for your protection. Do not use if outer neck seal or inner-seal is missing or damaged.

As with all dietary supplements, some individuals may not tolerate or may be allergic to the ingredients used.

Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult your physician if you have negative reactions upon ingestion.

Do not consume this product if you are pregnant or nursing.

Consult your physician for further information.

Formulation Notes

Formulated to be free of allergens derived from: Gluten, yeast, artificial colors and flavors.

Contains soy.

Additional Information

Label ID L-HOL780-919060-B Product #919060

KEEP CONTAINER TIGHTLY CLOSED. STORE AT ROOM TEMPERATURE.

Supports Optimal Adrenal Function

HOLTORF MEDICAL GROUP, INC. CENTERS FOR HORMONE IMBALANCE, HYPOTHYROIDISM AND FATIGUE

Suntheanine(R)

Vcaps(TM)

919.002

V1

Metadata

Product Details

UPC / SKU6 15033 60919 1
DSLD Entry Date2013-03-25
Product TypeOther Combinations
FormCapsule
DSLD ID19221
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
51
Avg Quality
16
Rct
14
Systematic Review
5
Clinical Trial
4
Meta Analysis
B The efficacy and safety of Chinese herbal medicine, Rhodiola formulation in treating ischemic heart disease: a systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2014 PubMed DOI
B Clinical evidence for the adaptogenic effects of Withania somnifera and Rhodiola rosea - A systematic review with molecular interpretation of psychometric outcomes
Systematic Review Annals of agricultural and environmental medicine : AAEM 2026 PubMed DOI
B Efficacy and safety of Rhodiola crenulata extract in the treatment of acute high altitude disease, based on studies involving populations in China: A systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
B The Impact of Rhodiola Rosea Extract on Strength Performance in Alternative Bench-Press and Bench-Pull Exercises Under Resting and Mental Fatigue Conditions: A Randomized, Triple-Blinded, Placebo-Controlled, Crossover Trial
Rct Nutrients 2025 PubMed DOI
B Liver function monitoring: a prospective nested case-control study of Salvia miltiorrhiza polyphenol injection
Meta Analysis Scientific reports 2020 PubMed DOI
B A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers
Rct Nutritional neuroscience 2022 PubMed DOI
B Standardized Rhodiola rosea injection for left ventricular remodeling and inflammation in patients with HFrEF: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Rhodiola rosea for physical and mental fatigue: a systematic review
Systematic Review BMC complementary and alternative medicine 2012 PubMed DOI
C Dazhu Hongjingtian Preparation as Adjuvant Therapy for Unstable Angina Pectoris: A Meta-Analysis of Randomized Controlled Trials
Systematic Review Frontiers in pharmacology 2020 PubMed DOI
C Understanding the research landscape of over-the-counter herbal products, dietary supplements, and medications evaluated for depressive symptoms in adults: a scoping review
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.