🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

3 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
60 mg (100% DV)
20 mg (1000% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 20mg UL 100mg
50 mcg (13% DV)
✅ Within RDA (0.1× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.05mg UL 1.0mg
50 mcg (833% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
100 mcg (143% DV)
✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.1mg UL 0.4mg
Liver Support Blend
Metabolism & Nutrient Transport
Antioxidant Support Complex

Other Ingredients

Cellulose Gelatin Titanium Dioxide FD&C Blue #1

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take three capsules daily with food.

⚠️ Warnings & Precautions

WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery.

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

No Artificial Flavors, No Wheat, No Gluten, Yeast Free.

Liver Support-Provides a specialized blend of ingredients know to help with lipid transport and metabolism, along with milk thistle known to have antioxidant properties and support healthy liver function.* Also includes picrorhiza and pantethine for added support.* Metabolism & Nutrient Transport-Contains B-complex vitamins, including choline and betaine, vitamins B-6 and B-12 and folic acid, which are required by the liver to help with nutrient transport and metabolism.* With premium, highly absorbable forms of vitamin B-6 an folic acid, along with betaine, an important amino acid, this formula supplies the highest quality fuel for reactions important for liver health.* Antioxidant Support-Contains powerful antioxidants to help minimize cellular damage.* Alpha-lipoic acid support the regeneration of other antioxidants in the body, and CoQ-10 functions as an important antioxidant that the body is also able to recycle and reuse.* Glutathione is a potent antioxidant that supports the antioxidant activity of vitamin C and also supports normal immune system function.* N-acetyl-l-cysteine supports the availability of glutathione.* Selenium is an essential mineral which helps build antioxidant enzymes in the body.* Both vitamin C and a clinically studied form of turmeric are also added for additional support.*

Additional Information

Please recycle this box.

Each premium formula is designed to be used in conjunction with your physician recommended healthcare regimen. This line of products is precisely formulated to provide clinical strength ingredients and additional nutrients that address key health concerns.

DEVELOPED WITH AND ENDORSED BY GNC MEDICAL ADVISORY BOARD ADVANCED KNOWLEDGE FOR BETTER HEALTH The GNC Medical Advisory Board utilizes their in-depth medical knowledge and experience to aid in the creation and ongoing development of GNC products, helping GNC stay on the forefront of product innovation and delivering on our commitment to helping you LIVE WELL.

This multi-action product is designed to supply nutrients to support a healthy liver and promote normal, healthy liver function.*

PHYSICIAN ENDORSED

CODE 714312 GNG

Conforms to USP <2091> for weight. Meets USP <2040> disintegration.

Store in a cool, dry place.

PM714312

GNC QUALITY COMMITMENT For more that 75 years, GNC has been the leader in the development and manufacture of dietary supplements and is committed to producing the most superior products. We use only the highest quality ingredients manufactured under the strictest quality controls. Every raw material used is tested to ensure its purity and potency. Each product is dated and then shipped immediately to our stores to ensure that you are purchasing the freshest supplements available.

Supports the liver's natural cleansing & detoxifying process* Protects liver cells from free radical damage with powerful antioxidants* Provides support for healthy liver enzyme activity & nutrient metabolism*

Setria(TM) The Power To Protect(TM)

Product Details

UPC / SKU 0 48107 11835 8
DSLD Entry Date 2013-02-25
Product Type Other Combinations
Form Capsule
DSLD ID 18450
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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